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NCT01997190 · ClinicalTrials.gov registry record · Phase 1
Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion
A Phase 1 study, sponsored by Candel Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
NCT01997190: Completed Phase 1 study, sponsored by Candel Therapeutics.
NCT01997190 is a Phase 1 study that has completed, run by Candel Therapeutics. The registered enrollment target is 19 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01997190, a Phase 1 study, has completed, sponsored by Candel Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
Study Summary
This is a phase I study of intrapleural AdV-tk therapy in patients with malignant pleural effusion (MPE). The primary objective is to test the safety of intrapleural AdV-tk therapy. Secondary objectives are to evaluate clinical efficacy and biologic activity
Interventions
- BIOLOGICAL AdV-tk + valacyclovir
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2013-10 |
| Est. Completion | 2018-02 |
| Phase | Phase 1 |
What the finished NCT01997190 record still lists
NCT01997190 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 1 intervention - of which AdV-tk + valacyclovir is the first listed.
NCT01997190 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01997190 about?
NCT01997190 is a clinical study titled "Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion". This is a phase I study of intrapleural AdV-tk therapy in patients with malignant pleural effusion (MPE). The primary objective is to test the safety of intrapleural AdV-tk therapy. Secondary objectives are to evaluate clinical efficacy and biologic activity
What is the current status of trial NCT01997190?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2013-10. Estimated completion is 2018-02.
What interventions are being tested in trial NCT01997190?
The interventions under investigation include: AdV-tk + valacyclovir (BIOLOGICAL).
Who is sponsoring clinical trial NCT01997190?
This trial is sponsored by Candel Therapeutics, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01997190's enrollment target sits among peer trials
19 1716th of 2000 higher than 281 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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