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NCT01996527 · ClinicalTrials.gov registry record · Early Phase 1
3T MRI Biomarkers of Glioma Treatment Response
A Early Phase 1 study, sponsored by Vanderbilt-Ingram Cancer Center.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 7
- Enrollment target
NCT01996527: Clinical Trial Early Phase 1 study, sponsored by Vanderbilt-Ingram Cancer Center.
NCT01996527 is a Early Phase 1 study that was terminated before completion, run by Vanderbilt-Ingram Cancer Center. The registered enrollment target is 7 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01996527, a Early Phase 1 study, was terminated before completion, sponsored by Vanderbilt-Ingram Cancer Center.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
This pilot clinical trial studies advanced magnetic resonance imaging (MRI) techniques in measuring treatment response in patients with high-grade glioma. New diagnostic procedures, such as advanced MRI techniques at 3 Tesla, may be more effective than standard MRI in measuring treatment response in patients receiving treatment for high-grade gliomas.
Primary Outcome
Number of patients in each response category, per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1, summarized as follows for target lesion criteria: complete response (CR),disappearance of target lesions; partial response (PR), \>=30% decrease in sum of longest diameter (LD) of target lesions; progressive disease (PD), \>=20% increase in sum of LD of target lesions or appearance of new lesions; stable disease (SD), insufficient change in target lesions or new lesions to qualify as eit
Interventions
- DEVICE DCE-MRI
- DEVICE 3-Tesla magnetic resonance imaging
- DEVICE CEST-MRI
- DEVICE DW-MRI
- DEVICE DSC-MRI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2012-05 |
| Est. Completion | 2016-01-01 |
| Phase | Early Phase 1 |
Why NCT01996527 stopped before completion
NCT01996527 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 5 interventions - of which DCE-MRI is the first listed.
NCT01996527 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01996527 about?
NCT01996527 is a clinical study titled "3T MRI Biomarkers of Glioma Treatment Response". This pilot clinical trial studies advanced magnetic resonance imaging (MRI) techniques in measuring treatment response in patients with high-grade glioma. New diagnostic procedures, such as advanced MRI techniques at 3 Tesla, may be more effective than standard MRI in measuring treatment response in...
What is the current status of trial NCT01996527?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 7 participants. The study started on 2012-05. Estimated completion is 2016-01-01.
What interventions are being tested in trial NCT01996527?
The interventions under investigation include: DCE-MRI (DEVICE), 3-Tesla magnetic resonance imaging (DEVICE), CEST-MRI (DEVICE), DW-MRI (DEVICE), DSC-MRI (DEVICE).
Who is sponsoring clinical trial NCT01996527?
This trial is sponsored by Vanderbilt-Ingram Cancer Center, which has 189 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01996527's enrollment target sits among peer trials
7 1825th of 2000 higher than 156 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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