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NCT01989949 · ClinicalTrials.gov registry record · Phase 1
Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women
A Phase 1 study, sponsored by Tetraphase Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT01989949: Completed Phase 1 study, sponsored by Tetraphase Pharmaceuticals.
NCT01989949 is a Phase 1 study that has completed, run by Tetraphase Pharmaceuticals. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01989949, a Phase 1 study, has completed, sponsored by Tetraphase Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
This is a phase 1, open-label, randomized pharmacokinetic and safety study in healthy adult subjects, who will undergo bronchoscopy and bronchoalveolar lavage (BAL) after receiving seven (7) doses of 1.0 mg/kg IV TP-434.
Interventions
- DRUG TP-434 (Eravacycline) reconstituted and administered via an IV infusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2012-11 |
| Est. Completion | 2013-04 |
| Phase | Phase 1 |
What the finished NCT01989949 record still lists
NCT01989949 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 1 intervention - of which TP-434 (Eravacycline) reconstituted and administered via an IV infusion is the first listed.
NCT01989949 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01989949 about?
NCT01989949 is a clinical study titled "Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women". This is a phase 1, open-label, randomized pharmacokinetic and safety study in healthy adult subjects, who will undergo bronchoscopy and bronchoalveolar lavage (BAL) after receiving seven (7) doses of 1.0 mg/kg IV TP-434.
What is the current status of trial NCT01989949?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2012-11. Estimated completion is 2013-04.
What interventions are being tested in trial NCT01989949?
The interventions under investigation include: TP-434 (Eravacycline) reconstituted and administered via an IV infusion (DRUG).
Who is sponsoring clinical trial NCT01989949?
This trial is sponsored by Tetraphase Pharmaceuticals, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01989949's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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