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NCT01988779 · ClinicalTrials.gov registry record · Phase 3

Oral Versus Topical Antibiotics for Chronic Rhinosinusitis Exacerbations

A Phase 3 study of Chronic Rhinosinusitis, sponsored by University of Rochester.

Completed
Registry status
Phase 3
Development phase
33
Enrollment target
1
Study location

NCT01988779 is a Phase 3 study of Chronic Rhinosinusitis that has completed, run by University of Rochester. The registered enrollment target is 33 participants, below the 182-participant average among 4 other Chronic Rhinosinusitis trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01988779, a Phase 3 study of Chronic Rhinosinusitis, has completed, sponsored by University of Rochester.

COMPLETED
Registry status
Phase 3
Development phase
33 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to treat patients with a diagnosis of chronic rhinosinusitis (CRS) and a history of bilateral endoscopic sinus surgery during times of worsening symptoms and signs of acute infection on nasal endoscopy with one of two treatments: (1) oral antibiotics and twice daily intranasal saline irrigations or (2) oral placebo and twice daily intranasal antibiotic irrigations. The two treatments will be compared to see if there is any difference in patient outcomes. This will help guide treatment strategies for patients with CRS in the future.

Conditions Studied

Interventions

  • DRUG oral levofloxacin
  • DRUG nebulized levofloxacin

Study Locations (1)

New York

  • University of Rochester Department of Otolaryngology Head and Neck Surgery - Rochester

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2013-10
Est. Completion 2020-12-31
Phase Phase 3

Sponsor

University of Rochester

636 total trials

What the Registry Record Tells You About NCT01988779

The ClinicalTrials.gov registry entry for NCT01988779 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 182-participant average among 4 other Chronic Rhinosinusitis trials with a reported enrollment target (82% lower). The listed sponsor is University of Rochester, which has 636 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Chronic Rhinosinusitis appearing as the primary indexed condition, and to 2 interventions - of which oral levofloxacin is the first listed.

NCT01988779 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT01988779 about?

NCT01988779 is a clinical study titled "Oral Versus Topical Antibiotics for Chronic Rhinosinusitis Exacerbations". The purpose of this study is to treat patients with a diagnosis of chronic rhinosinusitis (CRS) and a history of bilateral endoscopic sinus surgery during times of worsening symptoms and signs of acute infection on nasal endoscopy with one of two treatments: (1) oral antibiotics and twice daily intr...

What is the current status of trial NCT01988779?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 33 participants. The study started on 2013-10. Estimated completion is 2020-12-31.

What conditions does trial NCT01988779 study?

This clinical trial studies the following conditions: Chronic Rhinosinusitis.

What interventions are being tested in trial NCT01988779?

The interventions under investigation include: oral levofloxacin (DRUG), nebulized levofloxacin (DRUG).

Who is sponsoring clinical trial NCT01988779?

This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01988779 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.