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NCT01977859 · ClinicalTrials.gov registry record · Phase 1

BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects

A Phase 1 study, sponsored by AdventHealth Translational Research Institute.

Completed
Registry status
Phase 1
Development phase
4
Enrollment target

NCT01977859: Completed Phase 1 study, sponsored by AdventHealth Translational Research Institute.

NCT01977859 is a Phase 1 study that has completed, run by AdventHealth Translational Research Institute. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01977859, a Phase 1 study, has completed, sponsored by AdventHealth Translational Research Institute.

COMPLETED
Registry status
Phase 1
Development phase
4 participants
Enrollment target

Study Summary

The purpose of this study is to collect data to help researchers better understand the various causes of obesity, which may lead to the development of new obesity treatment options.

Primary Outcome

Blood samples will be obtained at baseline, during the infusion and after the termination of the infusion for measurement of levels of recombinant human BNP (rhBNP) and N-terminal pro-brain natriuretic peptide (NTpro-BNP).

Interventions

  • DRUG Saline
  • DRUG Nesiritide

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2013-11
Est. Completion 2017-02-28
Phase Phase 1

What the finished NCT01977859 record still lists

NCT01977859 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 2 interventions - of which Saline is the first listed.

NCT01977859 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01977859 about?

NCT01977859 is a clinical study titled "BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects". The purpose of this study is to collect data to help researchers better understand the various causes of obesity, which may lead to the development of new obesity treatment options.

What is the current status of trial NCT01977859?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2013-11. Estimated completion is 2017-02-28.

What interventions are being tested in trial NCT01977859?

The interventions under investigation include: Saline (DRUG), Nesiritide (DRUG).

Who is sponsoring clinical trial NCT01977859?

This trial is sponsored by AdventHealth Translational Research Institute, which has 54 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01977859's enrollment target sits among peer trials

4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01977859, the US trial registry maintained by the National Library of Medicine. NCT01977859 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.