Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01975792 · ClinicalTrials.gov registry record
Fetal Thymus Involution as a Predictor of Adverse Neonatal Outcomes
A clinical trial, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 125
- Enrollment target
NCT01975792: Completed study, sponsored by University of Pennsylvania.
NCT01975792 is a clinical trial that has completed, run by University of Pennsylvania. The registered enrollment target is 125 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01975792 has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 125 participants
- Enrollment target
Study Summary
The thymus gland is a specialized organ in the chest that plays a central role in the adaptive immune system throughout development until puberty. In response to stress, the fetal thymus gland may shrink, or involute. The investigators propose a prospective cohort study that will enroll pregnant women admitted to labor and delivery for the management of preterm labor and/or preterm premature rupture of membranes from 28-36 weeks gestation. Based on sonographic thymus measurements, the investigators will develop a clinical prediction tool to identify babies who are at increased risk for adverse neonatal outcomes. A reliable non-invasive predictor of adverse neonatal outcome using thymic ultrasound measurements has the potential to affect clinical management, improve outcomes for premature babies, and direct further research efforts.
Primary Outcome
Neonatal respiratory compromise defined as respiratory distress requiring any CPAP (continuous positive airway pressure) and or ventilator therapy.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 125 participants |
| Start Date | 2013-03 |
| Est. Completion | 2014-04 |
What the finished NCT01975792 record still lists
NCT01975792 is an observational study that tracks outcomes without assigning an intervention. The registered 125 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01975792 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01975792 about?
NCT01975792 is a clinical study titled "Fetal Thymus Involution as a Predictor of Adverse Neonatal Outcomes". The thymus gland is a specialized organ in the chest that plays a central role in the adaptive immune system throughout development until puberty. In response to stress, the fetal thymus gland may shrink, or involute. The investigators propose a prospective cohort study that will enroll pregnant wom...
What is the current status of trial NCT01975792?
This trial is currently completed. The enrollment target is 125 participants. The study started on 2013-03. Estimated completion is 2014-04.
Who is sponsoring clinical trial NCT01975792?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02717039 · 125 participants
Pharmacogenomics of Heparin-Induced Thrombocytopenia
- NCT02763033 · 125 participants · Phase 2
Dietary Manipulation of the Microbiome-metabolomic Axis for Mitigating GVHD in Allo HCT Patients
- NCT02793999 · 125 participants
Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia
- NCT03003299 · 125 participants · NA
PARTNER 3 Trial - Aortic Valve-in-Valve
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia