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NCT01974063 · ClinicalTrials.gov registry record
Alternate Nicotine Delivery Systems and Airway Epithelial Biology
A clinical trial, sponsored by Weill Medical College of Cornell University.
- Terminated
- Registry status
- 96
- Enrollment target
NCT01974063: Clinical Trial study, sponsored by Weill Medical College of Cornell University.
NCT01974063 is a clinical trial that was terminated before completion, run by Weill Medical College of Cornell University. The registered enrollment target is 96 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01974063 was terminated before completion, sponsored by Weill Medical College of Cornell University.
- TERMINATED
- Registry status
- 96 participants
- Enrollment target
Study Summary
Cigarette smoking evokes major changes in the biology of the airway epithelium, the cell population that takes the brunt of the stress of cigarette smoke and the cell population central to the pathogenesis of chronic obstructive pulmonary disease (COPD) and lung cancer. The focus of this study is to identify the differences that two popular alternative nicotine delivery strategies, shisha and electronic cigarettes, have on the airway epithelium compared to cigarette smoking. We hypothesize that both alternative nicotine delivery strategies disorder airway epithelial biology, but in different ways than does cigarette smoking.
Primary Outcome
We will measure the effect that shisha smoking has on the small airway epithelium (SAE) by measuring parameters such as the SAE gene expression, DNA methylation, telomere length and cilia length in "pure shisha smokers" (i.e., non-cigarette smokers.) We will compare these parameters to the same parameters measured in non-smokers and cigarette smokers.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2013-03 |
| Est. Completion | 2017-05 |
Why NCT01974063 stopped before completion
NCT01974063 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 96 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01974063 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01974063 about?
NCT01974063 is a clinical study titled "Alternate Nicotine Delivery Systems and Airway Epithelial Biology". Cigarette smoking evokes major changes in the biology of the airway epithelium, the cell population that takes the brunt of the stress of cigarette smoke and the cell population central to the pathogenesis of chronic obstructive pulmonary disease (COPD) and lung cancer. The focus of this study is to...
What is the current status of trial NCT01974063?
This trial is currently terminated. The enrollment target is 96 participants. The study started on 2013-03. Estimated completion is 2017-05.
Who is sponsoring clinical trial NCT01974063?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
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