Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01972139 · ClinicalTrials.gov registry record · NA

Renal Denervation in Patients With Uncontrolled Hypertension - SYMPLICITY HTN-4

A NA study, sponsored by Medtronic Vascular.

Completed
Registry status
NA
Development phase
44
Enrollment target

NCT01972139: Completed NA study, sponsored by Medtronic Vascular.

NCT01972139 is a NA study that has completed, run by Medtronic Vascular. The registered enrollment target is 44 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01972139, a NA study, has completed, sponsored by Medtronic Vascular.

COMPLETED
Registry status
NA
Development phase
44 participants
Enrollment target

Study Summary

An international, multi-center, prospective, blinded, randomized, controlled trial. The objective is to demonstrate that catheter-based renal denervation is an effective and safe treatment for uncontrolled hypertension.

Interventions

  • DEVICE Renal Angiography
  • DEVICE Renal Denervation using the Symplicity Renal Denervation System
  • OTHER Sham Renal Denervation

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2013-10
Est. Completion 2017-01
Phase NA
Medtronic Vascular

26 total trials

What the finished NCT01972139 record still lists

NCT01972139 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 3 interventions - of which Renal Angiography is the first listed.

NCT01972139 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01972139 about?

NCT01972139 is a clinical study titled "Renal Denervation in Patients With Uncontrolled Hypertension - SYMPLICITY HTN-4". An international, multi-center, prospective, blinded, randomized, controlled trial. The objective is to demonstrate that catheter-based renal denervation is an effective and safe treatment for uncontrolled hypertension.

What is the current status of trial NCT01972139?

This trial is currently completed. It is a NA study. The enrollment target is 44 participants. The study started on 2013-10. Estimated completion is 2017-01.

What interventions are being tested in trial NCT01972139?

The interventions under investigation include: Renal Angiography (DEVICE), Renal Denervation using the Symplicity Renal Denervation System (DEVICE), Sham Renal Denervation (OTHER).

Who is sponsoring clinical trial NCT01972139?

This trial is sponsored by Medtronic Vascular, which has 26 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01972139's enrollment target sits among peer trials

44 1423rd of 2000 higher than 566 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02323945 · 44 participants · NA

    Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury

  • NCT03093909 · 44 participants · Phase 1

    Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

  • NCT03104491 · 44 participants · Phase 1

    Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

  • NCT03781765 · 44 participants · Phase 4

    Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01972139, the US trial registry maintained by the National Library of Medicine. NCT01972139 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.