Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01955564 · ClinicalTrials.gov registry record · Phase 1

A Phase I- Sequential Cohort Dosing to Determine Maximum Tolerated Dose in Healthy Male Volunteers.

A Phase 1 study, sponsored by Newron Pharmaceuticals SPA.

Completed
Registry status
Phase 1
Development phase
54
Enrollment target

NCT01955564: Completed Phase 1 study, sponsored by Newron Pharmaceuticals SPA.

NCT01955564 is a Phase 1 study that has completed, run by Newron Pharmaceuticals SPA. The registered enrollment target is 54 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01955564, a Phase 1 study, has completed, sponsored by Newron Pharmaceuticals SPA.

COMPLETED
Registry status
Phase 1
Development phase
54 participants
Enrollment target

Study Summary

This is a prospective, 8-day, randomized, double-blind, placebo-controlled, sequential-cohort study designed to evaluate the safety, tolerability, and MTD of single escalating oral doses of NW-3509A in healthy male volunteers. Six independent cohorts of 12 volunteers each will participate in this study, with the first 9 volunteers in each cohort to qualify being randomized to receive study medication and the remaining 3 to be used as backups/ alternates. In each cohort, 6 subjects will be randomly assigned to receive NW-3509A and 3 subjects will receive placebo.

Primary Outcome

Physical examinations were carried out on the following: Lymph nodes, mouth, neck, nervous system, nose, skin and throat.

Interventions

  • DRUG NW-3509a

Trial Details

FieldValue
Enrollment Target 54 participants
Start Date 2013-06
Est. Completion 2015-02
Phase Phase 1
Newron Pharmaceuticals SPA

9 total trials

What the finished NCT01955564 record still lists

NCT01955564 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% lower).

The record links to 0 conditions, and to 1 intervention - of which NW-3509a is the first listed.

NCT01955564 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01955564 about?

NCT01955564 is a clinical study titled "A Phase I- Sequential Cohort Dosing to Determine Maximum Tolerated Dose in Healthy Male Volunteers.". This is a prospective, 8-day, randomized, double-blind, placebo-controlled, sequential-cohort study designed to evaluate the safety, tolerability, and MTD of single escalating oral doses of NW-3509A in healthy male volunteers. Six independent cohorts of 12 volunteers each will participate in this st...

What is the current status of trial NCT01955564?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 54 participants. The study started on 2013-06. Estimated completion is 2015-02.

What interventions are being tested in trial NCT01955564?

The interventions under investigation include: NW-3509a (DRUG).

Who is sponsoring clinical trial NCT01955564?

This trial is sponsored by Newron Pharmaceuticals SPA, which has 9 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01955564's enrollment target sits among peer trials

54 931st of 2000 higher than 1,053 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01269853 · 54 participants · Phase 1

    Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

  • NCT02390752 · 54 participants · Phase 1

    Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

  • NCT02991248 · 54 participants · NA

    Improve Dynamic Lateral Balance of Humans With SCI

  • NCT02993900 · 54 participants · NA

    Image-Guided Gynecologic Brachytherapy

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01955564, the US trial registry maintained by the National Library of Medicine. NCT01955564 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.