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NCT01954160 · ClinicalTrials.gov registry record · Phase 2
Study of Renal Denervation in Patients With Heart Failure
A Phase 2 study, sponsored by Adrian Hernandez.
- Terminated
- Registry status
- Phase 2
- Development phase
- 5
- Enrollment target
NCT01954160: Clinical Trial Phase 2 study, sponsored by Adrian Hernandez.
NCT01954160 is a Phase 2 study that was terminated before completion, run by Adrian Hernandez. The registered enrollment target is 5 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01954160, a Phase 2 study, was terminated before completion, sponsored by Adrian Hernandez.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 5 participants
- Enrollment target
Study Summary
Congestive heart failure is a common disorder in which the heart cannot pump enough blood to meet the needs of the rest of the body. Poor sodium handling by the kidneys is a damaging effect of heart failure, and it leads to symptoms of congestion such as shortness of breath or ankle swelling. Recent studies suggest that reducing the nerve activity to a kidney could reduce sodium retention and blood pressure. An improvement in the way the kidneys handle sodium may reduce disease progression and decrease symptoms for heart failure patients.
Primary Outcome
Within-subject comparison of increase in urine sodium excretion following saline loading before RSD and 13 weeks following RSD.
Interventions
- DEVICE Symplicity Renal Denervation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2013-12 |
| Est. Completion | 2014-12 |
| Phase | Phase 2 |
Why NCT01954160 stopped before completion
NCT01954160 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which Symplicity Renal Denervation is the first listed.
NCT01954160 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01954160 about?
NCT01954160 is a clinical study titled "Study of Renal Denervation in Patients With Heart Failure". Congestive heart failure is a common disorder in which the heart cannot pump enough blood to meet the needs of the rest of the body. Poor sodium handling by the kidneys is a damaging effect of heart failure, and it leads to symptoms of congestion such as shortness of breath or ankle swelling. Recent...
What is the current status of trial NCT01954160?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 5 participants. The study started on 2013-12. Estimated completion is 2014-12.
What interventions are being tested in trial NCT01954160?
The interventions under investigation include: Symplicity Renal Denervation (DEVICE).
Who is sponsoring clinical trial NCT01954160?
This trial is sponsored by Adrian Hernandez, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01954160's enrollment target sits among peer trials
5 2000th of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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