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NCT01951378 · ClinicalTrials.gov registry record · Phase 4

Comparison of Nebulizers in ED in Pediatric Asthma Patients

A Phase 4 study, sponsored by Seton Healthcare Family.

Terminated
Registry status
Phase 4
Development phase
40
Enrollment target

NCT01951378: Clinical Trial Phase 4 study, sponsored by Seton Healthcare Family.

NCT01951378 is a Phase 4 study that was terminated before completion, run by Seton Healthcare Family. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01951378, a Phase 4 study, was terminated before completion, sponsored by Seton Healthcare Family.

TERMINATED
Registry status
Phase 4
Development phase
40 participants
Enrollment target

Study Summary

The primary objective will be, in an open-label randomized trial, a comparison of emergency department (ED) length of stay (LOS) between children experiencing acute asthma treated with two different nebulizers. Secondary outcomes will include admission rates, hospital LOS, need for additional therapies, transfers to a higher level of care, side-effects, and unscheduled return visits

Primary Outcome

The primary endpoint will be mean ED LOS difference between the groups. Using historical data as a guide, we calculated a baseline LOS mean for discharged patients of 181 minutes, and standard deviation (SD) of 83 minutes. For this reason, an interim analysis will be conducted in order to assess a pilot sample for the purpose of estimating these values. 25 subjects in each arm (50 subjects total) will be enrolled during the initial phase of the study. This early phase interim analysis is not pow

Interventions

  • DRUG Albuterol
  • DEVICE Hudson RCI® nebulizer
  • DEVICE NebuTech® HDN® nebulizer

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2013-09
Est. Completion 2016-07
Phase Phase 4
Seton Healthcare Family

15 total trials

Why NCT01951378 stopped before completion

NCT01951378 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 3 interventions - of which Albuterol is the first listed.

NCT01951378 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01951378 about?

NCT01951378 is a clinical study titled "Comparison of Nebulizers in ED in Pediatric Asthma Patients". The primary objective will be, in an open-label randomized trial, a comparison of emergency department (ED) length of stay (LOS) between children experiencing acute asthma treated with two different nebulizers. Secondary outcomes will include admission rates, hospital LOS, need for additional therap...

What is the current status of trial NCT01951378?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2013-09. Estimated completion is 2016-07.

What interventions are being tested in trial NCT01951378?

The interventions under investigation include: Albuterol (DRUG), Hudson RCI® nebulizer (DEVICE), NebuTech® HDN® nebulizer (DEVICE).

Who is sponsoring clinical trial NCT01951378?

This trial is sponsored by Seton Healthcare Family, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01951378's enrollment target sits among peer trials

40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01951378, the US trial registry maintained by the National Library of Medicine. NCT01951378 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.