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NCT01948609 · ClinicalTrials.gov registry record
Prospective Research of Outcomes After Salpingo-oophorectomy
A clinical trial, sponsored by University of California, San Francisco.
- Completed
- Registry status
- 100
- Enrollment target
NCT01948609: Completed study, sponsored by University of California, San Francisco.
NCT01948609 is a clinical trial that has completed, run by University of California, San Francisco. The registered enrollment target is 100 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01948609 has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- 100 participants
- Enrollment target
Study Summary
PROSper is a prospective cohort study of 100 women 35-50 years of age with BRCA 1/2 mutations who have elected to either undergo risk reducing salpingo-oophorectomy (RRSO) or nonsurgical management. The investigators will compare the change in cardiovascular health, bone health, sexual function, quality of life, and menopausal symptoms over 3 years of follow-up between women who undergo RRSO (baseline just prior to surgery) and age-matched controls that do not undergo RRSO. The investigators hypothesis is that women who undergo a premature surgical menopause induced by RRSO have worse cardiovascular health and bone health compared with women who do not undergo RRSO.
Primary Outcome
We will use dual-energy x-ray absorptiometry (DEXA) scan results and Intima-media thickness of the carotid artery (IMT) testing to assess changes in bone mineral density and carotid artery intima media thickness, respectively.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2014-07 |
| Est. Completion | 2021-12 |
What the finished NCT01948609 record still lists
NCT01948609 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01948609 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01948609 about?
NCT01948609 is a clinical study titled "Prospective Research of Outcomes After Salpingo-oophorectomy". PROSper is a prospective cohort study of 100 women 35-50 years of age with BRCA 1/2 mutations who have elected to either undergo risk reducing salpingo-oophorectomy (RRSO) or nonsurgical management. The investigators will compare the change in cardiovascular health, bone health, sexual function, qua...
What is the current status of trial NCT01948609?
This trial is currently completed. The enrollment target is 100 participants. The study started on 2014-07. Estimated completion is 2021-12.
Who is sponsoring clinical trial NCT01948609?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
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