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NCT01940679 · ClinicalTrials.gov registry record · NA

Bioavailability of Encapsulated Omega-3 Fatty Acids

A NA study of Bioavailability of Omega-3s in Military Rations, sponsored by United States Army Research Institute of Environmental Medicine.

Completed
Registry status
NA
Development phase
14
Enrollment target
1
Study location

NCT01940679 is a NA study of Bioavailability of Omega-3s in Military Rations that has completed, run by United States Army Research Institute of Environmental Medicine. The registered enrollment target is 14 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT01940679, a NA study of Bioavailability of Omega-3s in Military Rations, has completed, sponsored by United States Army Research Institute of Environmental Medicine.

COMPLETED
Registry status
NA
Development phase
14 participants
Enrollment target
1
Study location

Study Summary

Omega-3 fatty acids (n-3s), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have anti-inflammatory properties and other documented beneficial health effects that could warrant n-3 fortification of combat rations. However, military combat rations must meet rigorous shelf-stability guidelines (e.g.,, 3 years at 80°F or 6 months at 100°F), which is problematic for natural food sources of n-3s (e.g., oil and fish), which degrade when exposed to high temperatures and prolonged shelf-storage. Encapsulation, e.g., coating freeze dried n-3s with gelatin, can prevent this degradation, and Natick Soldier Research, Development and Engineering Center's (NSRDEC) Combat Feeding Directorate used encapsulated n-3 technology to produce n-3 enriched ration items that withstand environmental stressors and meet shelf-life specifications for military rations. However, the bioavailability of the encapsulated n-3s in these rations is unknown, particularly when they are incorporated into high-protein food items and exposed to high temperatures and prolonged storage. In this randomized, cross-over study, civilian and/or military personnel will be asked to consume: 1) a high protein food item enriched with encapsulated n-3s (600 mg) and previously stored for 6 months at 100°F; 2) a low-protein food item enriched with encapsulated n-3s (600 mg) and previously stored for 6 months at 100°F; 3) a high protein food item with encapsulated n-3s (600 mg) that was not subjected to high-temperature and prolonged storage; and, 4) a low-protein food item with encapsulated n-3s (600 mg) that was not subjected to high temperature and prolonged storage. Serial blood sampling to measure acute changes in the circulating fatty acid profile will occur in the hour before and 6 hours after consumption of each ration component. The only known risks, which this study presents to participants, are those associated with venous catheter placement. The results will help military ration develop

Interventions

  • DIETARY_SUPPLEMENT encapsulated 600 mg EPA/DHA

Study Locations (1)

Massachusetts

  • U.S. Army Research Institute of Environmental Medicine - Natick

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2013-09
Est. Completion 2013-12
Phase NA

What the Registry Record Tells You About NCT01940679

The ClinicalTrials.gov registry entry for NCT01940679 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is United States Army Research Institute of Environmental Medicine, which has 59 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Bioavailability of Omega-3s in Military Rations appearing as the primary indexed condition, and to 1 intervention - of which encapsulated 600 mg EPA/DHA is the first listed.

NCT01940679 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT01940679 about?

NCT01940679 is a clinical study titled "Bioavailability of Encapsulated Omega-3 Fatty Acids". Omega-3 fatty acids (n-3s), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have anti-inflammatory properties and other documented beneficial health effects that could warrant n-3 fortification of combat rations. However, military combat rations must meet rigorous shelf-stab...

What is the current status of trial NCT01940679?

This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2013-09. Estimated completion is 2013-12.

What conditions does trial NCT01940679 study?

This clinical trial studies the following conditions: Bioavailability of Omega-3s in Military Rations.

What interventions are being tested in trial NCT01940679?

The interventions under investigation include: encapsulated 600 mg EPA/DHA (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT01940679?

This trial is sponsored by United States Army Research Institute of Environmental Medicine, which has 59 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01940679 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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