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NCT01939548 · ClinicalTrials.gov registry record · Phase 2

An Outpatient Study Of The Efficacy, Safety, And Tolerability Of PF-02545920 In The Adjunctive Treatment Of Sub-Optimally Controlled Symptoms of Schizophrenia

A Phase 2 study, sponsored by Pfizer.

Terminated
Registry status
Phase 2
Development phase
240
Enrollment target

NCT01939548: Clinical Trial Phase 2 study, sponsored by Pfizer.

NCT01939548 is a Phase 2 study that was terminated before completion, run by Pfizer. The registered enrollment target is 240 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01939548, a Phase 2 study, was terminated before completion, sponsored by Pfizer.

TERMINATED
Registry status
Phase 2
Development phase
240 participants
Enrollment target

Study Summary

This study aims to evaluate whether PF-02545920 is safe and effective in the treatment of sub-optimally controlled symptoms of schizophrenia during a 12-week outpatient treatment period. The study will use the Positive and Negative Syndrome Scale (PANSS) to measure change in symptoms for PF-02545920 from baseline compared to placebo.

Primary Outcome

The Positive and Negative Syndrome Scale (PANSS) assesses the positive symptoms, negative symptoms, and general psychopathology specifically associated with schizophrenia. The scale consists of 30 items. Each item is rated on a scale from 1 (symptom not present) to 7 (symptoms extremely severe). The sum of the 30 items is defined as the PANSS Total Score and ranges from 30 to 210; higher score indicates greater severity.

Interventions

  • DRUG Placebo
  • DRUG PF-02545920

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2013-10
Est. Completion 2014-10
Phase Phase 2
Pfizer

1,845 total trials

Why NCT01939548 stopped before completion

NCT01939548 is an interventional study that assigns participants to a tested intervention. The registered 240 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01939548 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01939548 about?

NCT01939548 is a clinical study titled "An Outpatient Study Of The Efficacy, Safety, And Tolerability Of PF-02545920 In The Adjunctive Treatment Of Sub-Optimally Controlled Symptoms of Schizophrenia". This study aims to evaluate whether PF-02545920 is safe and effective in the treatment of sub-optimally controlled symptoms of schizophrenia during a 12-week outpatient treatment period. The study will use the Positive and Negative Syndrome Scale (PANSS) to measure change in symptoms for PF-02545920...

What is the current status of trial NCT01939548?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2013-10. Estimated completion is 2014-10.

What interventions are being tested in trial NCT01939548?

The interventions under investigation include: Placebo (DRUG), PF-02545920 (DRUG).

Who is sponsoring clinical trial NCT01939548?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01939548's enrollment target sits among peer trials

240 239th of 2000 higher than 1,746 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01939548, the US trial registry maintained by the National Library of Medicine. NCT01939548 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.