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NCT01938950 · ClinicalTrials.gov registry record · NA

Resistance and Cardiorespiratory Time-matched Exercise in Youth: A Randomized Clinical Trial (RCT:RCT)

A NA study, sponsored by University of Pittsburgh.

Terminated
Registry status
NA
Development phase
118
Enrollment target

NCT01938950 is a NA study that was terminated before completion, run by University of Pittsburgh. The registered enrollment target is 118 participants.

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The verdict

NCT01938950, a NA study, was terminated before completion, sponsored by University of Pittsburgh.

TERMINATED
Registry status
NA
Development phase
118 participants
Enrollment target

Study Summary

The current epidemic rate of childhood obesity is a leading health concern as overweight/obese youth may suffer from comorbid conditions, once considered exclusive to adults. It has been suggested that physical inactivity is a major determinant of obesity and obesity-related health risk in children and adolescents. Recent studies in adults report that the combination of aerobic and resistance exercise is a better strategy than aerobic or resistance exercise alone for reducing risk factors for type 2 diabetes. Currently, the most effective exercise modality for concurrent reductions of adiposity, in particular abdominal fat, and risk factors for type 2 diabetes and cardiovascular disease (CVD) is unknown in adolescents. Therefore, we will employ a randomized trial to examine the effects of a long-term aerobic exercise, resistance exercise, and a combination of both exercise regimens on: 1) in vivo insulin sensitivity, glucose tolerance and risk for type 2 diabetes, 2) total adiposity, skeletal muscle mass, visceral adiposity and ectopic fat in the liver and skeletal muscle, and 3) traditional and non-traditional risk factors/markers for CVD in overweight boys and girls. We will recruit 168 sedentary overweight (BMI \>85th percentile) adolescent boys and girls aged 12-17 years old and randomly assign them to one of three 6-month intervention groups (n = 56 each group): 1) aerobic exercise (180 min/week), 2) resistance exercise (180 min/week), or 3) aerobic and resistance exercise (180 min/week) group. A weight maintenance diet (55-60% carbohydrate, 15-20% protein, and 25-30% fat) will be prescribed and monitored for all groups, so that any changes in energy balance will be induced by exercise intervention alone (e.g., no calorie restriction). We believe that this proposed application will have a significant implication that is directly relevant for one in three American adolescents who are at increased risk of developing obesity-related co-morbidities.

Interventions

  • OTHER Aerobic Exercise
  • OTHER Resistance Exercise
  • OTHER Aerobic and Resistance Exercise

Trial Details

FieldValue
Enrollment Target 118 participants
Start Date 2013-10
Est. Completion 2017-06-21
Phase NA

Sponsor

University of Pittsburgh

1,238 total trials

What the Registry Record Tells You About NCT01938950

The ClinicalTrials.gov registry entry for NCT01938950 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 118 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Aerobic Exercise is the first listed.

NCT01938950 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01938950 about?

NCT01938950 is a clinical study titled "Resistance and Cardiorespiratory Time-matched Exercise in Youth: A Randomized Clinical Trial (RCT:RCT)". The current epidemic rate of childhood obesity is a leading health concern as overweight/obese youth may suffer from comorbid conditions, once considered exclusive to adults. It has been suggested that physical inactivity is a major determinant of obesity and obesity-related health risk in children ...

What is the current status of trial NCT01938950?

This trial is currently terminated. It is a NA study. The enrollment target is 118 participants. The study started on 2013-10. Estimated completion is 2017-06-21.

What interventions are being tested in trial NCT01938950?

The interventions under investigation include: Aerobic Exercise (OTHER), Resistance Exercise (OTHER), Aerobic and Resistance Exercise (OTHER).

Who is sponsoring clinical trial NCT01938950?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.