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NCT01938040 · ClinicalTrials.gov registry record · Phase 4
Effect IV Ibuprofen and Inflammatory Responses
A Phase 4 study, sponsored by University of Medicine and Dentistry of New Jersey.
- Completed
- Registry status
- Phase 4
- Development phase
- 60
- Enrollment target
NCT01938040: Completed Phase 4 study, sponsored by University of Medicine and Dentistry of New Jersey.
NCT01938040 is a Phase 4 study that has completed, run by University of Medicine and Dentistry of New Jersey. The registered enrollment target is 60 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01938040, a Phase 4 study, has completed, sponsored by University of Medicine and Dentistry of New Jersey.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 60 participants
- Enrollment target
Study Summary
This study is being done because the investigators wish to study ways to improve recovery after surgery. Injury, including surgical injury, causes inflammation. Inflammation is the body's attempt to protect itself and to start the healing process. Some surgical complications are related to the body's natural inflammatory response. Although mainly a healing response, inflammation can also have side effects which delay recovery. The investigators wish to determine the effect of a medication known as ibuprofen on recovery. You may know ibuprofen by the name Advil or Motrin. The medication will be given through the vein prior to the start of the surgery. Three blood samples will be taken, two while the patient is under anesthesia. The subject will be asked to complete several questionnaires.
Primary Outcome
Serum concentration of cortisol, CRP, drawn in Post Anesthesia Care unit at 2 hours following surgery were compared with those same levels drawn preoperatively and intraoperatively.
Interventions
- DRUG ibuprofen
- OTHER sugar water/placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2013-05 |
| Est. Completion | 2014-08 |
| Phase | Phase 4 |
What the finished NCT01938040 record still lists
NCT01938040 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 2 interventions - of which ibuprofen is the first listed.
NCT01938040 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01938040 about?
NCT01938040 is a clinical study titled "Effect IV Ibuprofen and Inflammatory Responses". This study is being done because the investigators wish to study ways to improve recovery after surgery. Injury, including surgical injury, causes inflammation. Inflammation is the body's attempt to protect itself and to start the healing process. Some surgical complications are related to the body'...
What is the current status of trial NCT01938040?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2013-05. Estimated completion is 2014-08.
What interventions are being tested in trial NCT01938040?
The interventions under investigation include: ibuprofen (DRUG), sugar water/placebo (OTHER).
Who is sponsoring clinical trial NCT01938040?
This trial is sponsored by University of Medicine and Dentistry of New Jersey, which has 88 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01938040's enrollment target sits among peer trials
60 1125th of 2000 higher than 799 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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