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NCT01936948 · ClinicalTrials.gov registry record · NA

Safety of Endoscopic Resection of Large Colorectal Polyps: A Randomized Trial.

A NA study, sponsored by White River Junction Veterans Affairs Medical Center.

Completed
Registry status
NA
Development phase
928
Enrollment target

NCT01936948 is a NA study that has completed, run by White River Junction Veterans Affairs Medical Center. The registered enrollment target is 928 participants.

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The verdict

NCT01936948, a NA study, has completed, sponsored by White River Junction Veterans Affairs Medical Center.

COMPLETED
Registry status
NA
Development phase
928 participants
Enrollment target

Study Summary

The effectiveness of colonoscopy in reducing colorectal cancer mortality relies on the detection and removal of neoplastic polyps. Because the risk of prevalent cancer and of transition to cancer increases with polyp size, effective and safe resection of large polyps is particularly important. Large polyps ≥20mm are removed by so-called endoscopic mucosal resection (EMR) using electrocautery snares. Resection of these large polyps is associated with a risk of severe complications that may require hospitalization and additional interventions. The most common risk is delayed bleeding which is observed in approximately 2-9% of patients. A recent retrospective study suggests that closure of the large mucosal defect after resection may decrease the risk of delayed bleeding. However, significant uncertainty remains about the polypectomy techniques to optimizing resection and minimizing risk. Important aspects that may affect risk include clipping of the mucosal defect and electrocautery setting.

Interventions

  • PROCEDURE Clip closure

Trial Details

FieldValue
Enrollment Target 928 participants
Start Date 2013-04
Est. Completion 2022-10
Phase NA

What the Registry Record Tells You About NCT01936948

The ClinicalTrials.gov registry entry for NCT01936948 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 928 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is White River Junction Veterans Affairs Medical Center, which has 15 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Clip closure is the first listed.

NCT01936948 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01936948 about?

NCT01936948 is a clinical study titled "Safety of Endoscopic Resection of Large Colorectal Polyps: A Randomized Trial.". The effectiveness of colonoscopy in reducing colorectal cancer mortality relies on the detection and removal of neoplastic polyps. Because the risk of prevalent cancer and of transition to cancer increases with polyp size, effective and safe resection of large polyps is particularly important. Large...

What is the current status of trial NCT01936948?

This trial is currently completed. It is a NA study. The enrollment target is 928 participants. The study started on 2013-04. Estimated completion is 2022-10.

What interventions are being tested in trial NCT01936948?

The interventions under investigation include: Clip closure (PROCEDURE).

Who is sponsoring clinical trial NCT01936948?

This trial is sponsored by White River Junction Veterans Affairs Medical Center, which has 15 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.