Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01932983 · ClinicalTrials.gov registry record
Clinical Application of "Train of Four" Testing in the Intraoperative Monitoring Setting
A clinical trial, sponsored by NYU Langone Health.
- Completed
- Registry status
- 150
- Enrollment target
NCT01932983: Completed study, sponsored by NYU Langone Health.
NCT01932983 is a clinical trial that has completed, run by NYU Langone Health. The registered enrollment target is 150 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01932983 has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- 150 participants
- Enrollment target
Study Summary
The study examines the clinical application of TOF (train of four test) used by anesthesiologists and neurophysiologists during instrumented spine procedures, as well as certain associated parameters. 'Train of four' test is a test routinely used during the surgery, which is performed by stimulation of peripheral nerve with purpose to determine the degree of muscle relaxation by interpretation of muscle response. During spine surgery, it is helpful for the surgeon to have a patient's muscles as relaxed as possible with the least amount of tone, especially when exposing. Anesthesiologists achieve this level of relaxation by giving a neuromuscular blocking agent. If medication given to do this has not fully left their system by the time the surgeon needs to start putting in the screws and rods, then the intraoperative monitoring can not be adequately performed. If the muscles are too relaxed, then free run EMG and screw stimulation, two monitoring methods used, will not be analyzed correctly and the surgery may be adversely affected. This study compares the results of the 'train of four' test performed by neurophysiologists and anesthesiologists. Additionally, it looks at the differences, if any, in comparing stimulation of the foot nerve (tibial n.) or hand nerve (ulnar n.) Performing the TOF (train of four test) in the lower extremity can be relevant for many reasons. Train of four tests can show the presence of four twitches in the arms but the legs may not fully recovered from muscle relaxant given by anesthesia. Also, train of four test which uses subjective method of interpretation by anesthesiologists may present different results compared than objective quantitative method of train of four test interpretation. Ultimately, the goal of this study is to show the importance of 'TOF' testing in ensuring that any identifiable preventable intraoperative surgical complication is appropriately identified.
Primary Outcome
TOF test is performed after pedicle screw placement during lumbar spine surgery, prior neurophysiological pedicle screw position test.
Interventions
- DEVICE Train of four test
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2012-04 |
| Est. Completion | 2013-04 |
What the finished NCT01932983 record still lists
NCT01932983 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Train of four test is the first listed.
NCT01932983 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01932983 about?
NCT01932983 is a clinical study titled "Clinical Application of "Train of Four" Testing in the Intraoperative Monitoring Setting". The study examines the clinical application of TOF (train of four test) used by anesthesiologists and neurophysiologists during instrumented spine procedures, as well as certain associated parameters. 'Train of four' test is a test routinely used during the surgery, which is performed by stimulation...
What is the current status of trial NCT01932983?
This trial is currently completed. The enrollment target is 150 participants. The study started on 2012-04. Estimated completion is 2013-04.
What interventions are being tested in trial NCT01932983?
The interventions under investigation include: Train of four test (DEVICE).
Who is sponsoring clinical trial NCT01932983?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00412594 · 150 participants · Phase 2
Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia
- NCT01484730 · 150 participants
A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
- NCT01985919 · 150 participants
Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples
- NCT02016248 · 150 participants · NA
SBRT Boost for Unfavorable Prostate Cancer'
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia