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NCT01929980 · ClinicalTrials.gov registry record · Phase 2

Bortezomib to Treat Significant Complication of HSCT

A Phase 2 study, sponsored by Children's Hospital Medical Center, Cincinnati.

Completed
Registry status
Phase 2
Development phase
4
Enrollment target

NCT01929980: Completed Phase 2 study, sponsored by Children's Hospital Medical Center, Cincinnati.

NCT01929980 is a Phase 2 study that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 4 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01929980, a Phase 2 study, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.

COMPLETED
Registry status
Phase 2
Development phase
4 participants
Enrollment target

Study Summary

The purpose of this trial is to study the safety and effectiveness of a drug called Bortezomib for the treatment of low blood cell counts after bone marrow transplant.

Primary Outcome

For Autoimmune Hemolytic Anemia- At least 3 of 5 criteria should be met. 1. Stabilization of hemoglobin without transfusions by 2 weeks 2. Conversion of DAT from + to - by 6 weeks 3. Normalization of serum haptoglobin levels by 6 weeks 4. Normalization of indirect bilirubin levels by 6 weeks 5. Reduction in the frequency of transfusions by 50% by 4 weeks For Autoimmune Neutropenia- At least 2 of 3 criteria should be met. 1. Stabilization of absolute neutrophil count by 2 weeks 2. Undetectable

Interventions

  • DRUG Bortezomib

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2012-07
Est. Completion 2014-05
Phase Phase 2

What the finished NCT01929980 record still lists

NCT01929980 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 1 intervention - of which Bortezomib is the first listed.

NCT01929980 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01929980 about?

NCT01929980 is a clinical study titled "Bortezomib to Treat Significant Complication of HSCT". The purpose of this trial is to study the safety and effectiveness of a drug called Bortezomib for the treatment of low blood cell counts after bone marrow transplant.

What is the current status of trial NCT01929980?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2012-07. Estimated completion is 2014-05.

What interventions are being tested in trial NCT01929980?

The interventions under investigation include: Bortezomib (DRUG).

Who is sponsoring clinical trial NCT01929980?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01929980's enrollment target sits among peer trials

4 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01929980, the US trial registry maintained by the National Library of Medicine. NCT01929980 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.