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NCT01928381 · ClinicalTrials.gov registry record · Phase 2

Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Ability

A Phase 2 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 2
Development phase
150
Enrollment target

NCT01928381 is a Phase 2 study that has completed, run by AstraZeneca. The registered enrollment target is 150 participants.

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The verdict

NCT01928381, a Phase 2 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 2
Development phase
150 participants
Enrollment target

Study Summary

This is a 2-part study. In Part 1 of the study, subjects will undergo a pain reporting training program in which a painful stimulus will be applied to the subject's hand, and the subjects will be asked to report how painful the stimulus is. Over the course of the pain training sessions, feedback will be provided to the subject about how accurately they are reporting their degree of pain, relative to the amount of pressure stimulus applied to evoke pain. Those subjects who have adequate pain reporting ability will be asked to continue into Part 2 of the study in which 3 different blinded study drugs will be administered to each subject, in a crossover design to compare whether or not the study drugs improve pain associated with diabetic neuropathy.

Interventions

  • DRUG Placebo
  • DRUG AZD5213 + pregabalin
  • DRUG pregabalin capsules

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2013-11
Est. Completion 2015-05
Phase Phase 2

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT01928381

The ClinicalTrials.gov registry entry for NCT01928381 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT01928381 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01928381 about?

NCT01928381 is a clinical study titled "Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Ability". This is a 2-part study. In Part 1 of the study, subjects will undergo a pain reporting training program in which a painful stimulus will be applied to the subject's hand, and the subjects will be asked to report how painful the stimulus is. Over the course of the pain training sessions, feedback wil...

What is the current status of trial NCT01928381?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 150 participants. The study started on 2013-11. Estimated completion is 2015-05.

What interventions are being tested in trial NCT01928381?

The interventions under investigation include: Placebo (DRUG), AZD5213 + pregabalin (DRUG), pregabalin capsules (DRUG).

Who is sponsoring clinical trial NCT01928381?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.