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NCT01911195 · ClinicalTrials.gov registry record · NA
Reconstructing Consciousness and Cognition
A NA study, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT01911195 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 60 participants.
The verdict
NCT01911195, a NA study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
Currently it is unknown how the human brain reorganizes its network organization to generate conscious experience and cognitive activity after a period of unconsciousness. Therefore, the purpose of this study is to assess how cognitive activity is reconstructed after general anesthesia. The investigators hypothesize that the brain's transition from unconsciousness to consciousness and full cognition is a complex process that occurs over an extended period of time. Specifically, the investigators hypothesize the following order of cognitive reconstitution: responsiveness to command, attention, complex scanning and visual tracking, working memory, and executive function. Volunteers will be healthy participants who are anesthetized with commonly used anesthetic drugs as well as a non-anesthetized group to control for circadian influences. A total of 60 subjects will be recruited for this study. All subjects (male and female) will perform basic tests for cognition on a laptop computer at 30-minute intervals during this study. The testing battery to be administered was assembled to assess multiple cognitive functions in order to determine whether and how cognitive processes return to baseline function. Electroencephalogram (measuring brain electrical activity) data will be monitored and recorded during both anesthesia and cognitive testing, for subsequent analysis. This study is significant because it could lead to a better understanding of the neural correlates of human consciousness, as well as normal and abnormal conscious state transitions (including barriers to such transitions).
Interventions
- DRUG ISOFLURANE- Experimental Arm
- OTHER Control Group: Cognitive Testing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2013-07 |
| Est. Completion | 2015-02-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01911195
The ClinicalTrials.gov registry entry for NCT01911195 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which ISOFLURANE- Experimental Arm is the first listed.
NCT01911195 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01911195 about?
NCT01911195 is a clinical study titled "Reconstructing Consciousness and Cognition". Currently it is unknown how the human brain reorganizes its network organization to generate conscious experience and cognitive activity after a period of unconsciousness. Therefore, the purpose of this study is to assess how cognitive activity is reconstructed after general anesthesia. The investig...
What is the current status of trial NCT01911195?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2013-07. Estimated completion is 2015-02-09.
What interventions are being tested in trial NCT01911195?
The interventions under investigation include: ISOFLURANE- Experimental Arm (DRUG), Control Group: Cognitive Testing (OTHER).
Who is sponsoring clinical trial NCT01911195?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
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