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NCT01909947 · ClinicalTrials.gov registry record
Prediction of Extubation Readiness in Extreme Preterm Infants by the Automated Analysis of CardioRespiratory Behavior
A clinical trial of Prediction of Extubation Readiness, sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre.
- Completed
- Registry status
- 266
- Enrollment target
- 5
- Study locations
NCT01909947 is a study of Prediction of Extubation Readiness that has completed, run by McGill University Health Centre/Research Institute of the McGill University Health Centre. The registered enrollment target is 266 participants. The trial reports 5 study locations across 3 states.
The verdict
NCT01909947, a study of Prediction of Extubation Readiness, has completed, sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre.
- COMPLETED
- Registry status
- 266 participants
- Enrollment target
- 5
- Study locations
Study Summary
The investigators hypothesize that machine learning methods using a combination of novel, quantitative measures of cardio-respiratory variability can accurately predict the optimal time to extubate extreme preterm infants. In this multicenter prospective study, cardiorespiratory signals will be recorded from 250 extreme preterm infants who are eligible for extubation. Automated signal analysis algorithms will compute a variety of metrics for each infant describing the cardiorespiratory state. Machine learning methods will then be used to find the optimal combination of these statistical measures and clinical features that provide the best overall predictor of extubation readiness. Finally, investigators will develop an Automated system for Prediction of EXtubation (APEX) that will integrate the software for data acquisition, signal analysis, and outcome prediction into a single application suitable for use by medical personnel in the Neonatal Intensive Care Unit (NICU). The performance of APEX will later be clinically validated in 50 additional infants prospectively.
Conditions Studied
Interventions
- OTHER Cardiorespiratory signal acquisition
Study Locations (5)
Quebec
- Royal Victoria Hospital - Montreal
- Montreal Children's Hospital - Montreal
- Jewish General Hospital - Montreal
Michigan
- Wayne State University - Detroit
Rhode Island
- Women and Infants Hospital of Rhode Island - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 266 participants |
| Start Date | 2013-09 |
| Est. Completion | 2018-12 |
Sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre9 total trials
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01909947
The ClinicalTrials.gov registry entry for NCT01909947 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 266 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is McGill University Health Centre/Research Institute of the McGill University Health Centre, which has 9 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Prediction of Extubation Readiness appearing as the primary indexed condition, and to 1 intervention - of which Cardiorespiratory signal acquisition is the first listed.
NCT01909947 reports 5 study locations spanning 3 distinct geographic areas - top geographies include Quebec, Michigan, Rhode Island.
Frequently Asked Questions
What is clinical trial NCT01909947 about?
NCT01909947 is a clinical study titled "Prediction of Extubation Readiness in Extreme Preterm Infants by the Automated Analysis of CardioRespiratory Behavior". The investigators hypothesize that machine learning methods using a combination of novel, quantitative measures of cardio-respiratory variability can accurately predict the optimal time to extubate extreme preterm infants. In this multicenter prospective study, cardiorespiratory signals will be reco...
What is the current status of trial NCT01909947?
This trial is currently completed. The enrollment target is 266 participants. The study started on 2013-09. Estimated completion is 2018-12.
What conditions does trial NCT01909947 study?
This clinical trial studies the following conditions: Prediction of Extubation Readiness.
What interventions are being tested in trial NCT01909947?
The interventions under investigation include: Cardiorespiratory signal acquisition (OTHER).
Who is sponsoring clinical trial NCT01909947?
This trial is sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01909947 being conducted?
This trial has 5 study locations across Michigan, Rhode Island, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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