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NCT01908413 · ClinicalTrials.gov registry record · Phase 1
Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-427 When Given to Patients With Advanced and Refractory Solid Tumors or Lymphoma
A Phase 1 study, sponsored by Curis.
- Terminated
- Registry status
- Phase 1
- Development phase
- 23
- Enrollment target
NCT01908413: Clinical Trial Phase 1 study, sponsored by Curis.
NCT01908413 is a Phase 1 study that was terminated before completion, run by Curis. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01908413, a Phase 1 study, was terminated before completion, sponsored by Curis.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 23 participants
- Enrollment target
Study Summary
This is a phase I, open-label, dose-escalation study of CUDC-427 in patients with advanced or refractory solid tumors or lymphoma. CUDC-427 is a drug that is designed to antagonize proteins that prevent or interfere with cell death. The study is designed to assess the safety, including the maximum tolerated dose, the pharmacokinetics, and the anti-cancer activity of CUDC-427.
Interventions
- DRUG CUDC-427
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2013-07 |
| Est. Completion | 2015-11 |
| Phase | Phase 1 |
Why NCT01908413 stopped before completion
NCT01908413 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 1 intervention - of which CUDC-427 is the first listed.
NCT01908413 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01908413 about?
NCT01908413 is a clinical study titled "Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-427 When Given to Patients With Advanced and Refractory Solid Tumors or Lymphoma". This is a phase I, open-label, dose-escalation study of CUDC-427 in patients with advanced or refractory solid tumors or lymphoma. CUDC-427 is a drug that is designed to antagonize proteins that prevent or interfere with cell death. The study is designed to assess the safety, including the maximum t...
What is the current status of trial NCT01908413?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2013-07. Estimated completion is 2015-11.
What interventions are being tested in trial NCT01908413?
The interventions under investigation include: CUDC-427 (DRUG).
Who is sponsoring clinical trial NCT01908413?
This trial is sponsored by Curis, which has 12 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01908413's enrollment target sits among peer trials
23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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