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NCT01906346 · ClinicalTrials.gov registry record · Early Phase 1
Impact of a Non-Drug Choice on Cocaine Reinforcement
A Early Phase 1 study, sponsored by Joshua A. Lile, Ph.D..
- Completed
- Registry status
- Early Phase 1
- Development phase
- 9
- Enrollment target
NCT01906346: Completed Early Phase 1 study, sponsored by Joshua A. Lile, Ph.D..
NCT01906346 is a Early Phase 1 study that has completed, run by Joshua A. Lile, Ph.D.. The registered enrollment target is 9 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01906346, a Early Phase 1 study, has completed, sponsored by Joshua A. Lile, Ph.D..
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
Cocaine-use disorders continue to be a significant public health concern, yet no effective medications have been identified. The goal of this study is to establish a research platform for the development of medications for treatment of cocaine abuse and dependence. This study will incorporate self-administration procedures and a non-drug alternative reinforcer, which is hypothesized to reduce the reinforcing effects of cocaine.
Primary Outcome
The reinforcing effects of cocaine were determined using a modified progressive ratio procedure in which subjects made 9 choices between each available cocaine dose and one of three money alternatives.
Interventions
- DRUG Placebo
- DRUG Cocaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2014-01 |
| Est. Completion | 2015-06 |
| Phase | Early Phase 1 |
What the finished NCT01906346 record still lists
NCT01906346 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01906346 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01906346 about?
NCT01906346 is a clinical study titled "Impact of a Non-Drug Choice on Cocaine Reinforcement". Cocaine-use disorders continue to be a significant public health concern, yet no effective medications have been identified. The goal of this study is to establish a research platform for the development of medications for treatment of cocaine abuse and dependence. This study will incorporate self-a...
What is the current status of trial NCT01906346?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 9 participants. The study started on 2014-01. Estimated completion is 2015-06.
What interventions are being tested in trial NCT01906346?
The interventions under investigation include: Placebo (DRUG), Cocaine (DRUG).
Who is sponsoring clinical trial NCT01906346?
This trial is sponsored by Joshua A. Lile, Ph.D., which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01906346's enrollment target sits among peer trials
9 1746th of 2000 higher than 219 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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