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NCT01898949 · ClinicalTrials.gov registry record · NA
Stimulation of Diet-Induced Thermogenesis by Cold-Exposure
A NA study, sponsored by Pennington Biomedical Research Center.
- Completed
- Registry status
- NA
- Development phase
- 9
- Enrollment target
NCT01898949: Completed NA study, sponsored by Pennington Biomedical Research Center.
NCT01898949 is a NA study that has completed, run by Pennington Biomedical Research Center. The registered enrollment target is 9 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01898949, a NA study, has completed, sponsored by Pennington Biomedical Research Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
Study Summary
Human fat tissue is essentially white fat, the main function of which is to store excess energy intake, and to release it when necessary. Brown fat is far less abundant and is present in the body to burn fat (and thus energy) to generate heat to maintain body temperature around 96 degrees. This phenomenon is called thermogenesis. When humans are exposed to cold on a chronic basis, brown fat expands and becomes more active, and consequently burns more energy. The amount of brown fat is higher during winter, and daily short (20 minutes) exposures to cold might be sufficient to induce its activity. We hypothesized that daily short term (20 minutes) exposure to a cold environment (4 °C) for four weeks increases adaptive BAT-mediated thermogenesis. CIT and DIT will be increased proportionally (the increase in CIT and DIT will be correlated).
Primary Outcome
Change in energy expenditure is measured within 24 hours (acute) and after 4 weeks (chronic) of cold exposure with either bed-side calorimeter or whole-room calorimeter.
Interventions
- OTHER Cold Exposure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2010-11 |
| Est. Completion | 2012-05 |
| Phase | NA |
What the finished NCT01898949 record still lists
NCT01898949 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Cold Exposure is the first listed.
NCT01898949 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01898949 about?
NCT01898949 is a clinical study titled "Stimulation of Diet-Induced Thermogenesis by Cold-Exposure". Human fat tissue is essentially white fat, the main function of which is to store excess energy intake, and to release it when necessary. Brown fat is far less abundant and is present in the body to burn fat (and thus energy) to generate heat to maintain body temperature around 96 degrees. This phen...
What is the current status of trial NCT01898949?
This trial is currently completed. It is a NA study. The enrollment target is 9 participants. The study started on 2010-11. Estimated completion is 2012-05.
What interventions are being tested in trial NCT01898949?
The interventions under investigation include: Cold Exposure (OTHER).
Who is sponsoring clinical trial NCT01898949?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01898949's enrollment target sits among peer trials
9 1975th of 2000 higher than 25 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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