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NCT01898689 · ClinicalTrials.gov registry record · Phase 4
Optimizing Local Anesthetic Concentration for Continuous Popliteal-Sciatic Nerve Blocks
A Phase 4 study, sponsored by University of California, San Diego.
- Completed
- Registry status
- Phase 4
- Development phase
- 24
- Enrollment target
NCT01898689 is a Phase 4 study that has completed, run by University of California, San Diego. The registered enrollment target is 24 participants.
The verdict
NCT01898689, a Phase 4 study, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 24 participants
- Enrollment target
Study Summary
A continuous peripheral nerve block-also termed "perineural local anesthetic infusion"-involves the insertion of a tiny tube (a "catheter") through the skin and adjacent to a peripheral nerve, followed by local anesthetic (numbing medicine) administration via the catheter, providing pain control following surgery. Continuous peripheral nerve blocks may be provided in the hospital setting, but the use of lightweight, portable pumps permits infusion at home as well. However, it remains unknown if the concentration of the local anesthetic influences the block effects; or, is it rather simply the total dose of medication that is important. If it is the latter, then the concentration of local anesthetic could be increased, allowing a decreased basal infusion rate, which would allow patients at home to receive twice the duration of potent pain control since their infusion pump local anesthetic reservoir would last twice as long as current practice. In addition, if one concentration/dose combination results in less muscle weakness, but with at least equivalent analgesia, then the risk of falling might be decreased as well. The investigators will test the hypothesis that providing ropivacaine at different concentrations and rates (0.1% at 8 mL/hour vs. 0.4% at 2 mL/hour)-but at an equivalent total basal (8 mg/hour)-produces comparable effects when used in a continuous popliteal-sciatic nerve block.
Interventions
- DRUG Ropivacaine 0.1%
- DRUG Ropivacaine 0.4%
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2013-07 |
| Est. Completion | 2013-11 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01898689
The ClinicalTrials.gov registry entry for NCT01898689 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Ropivacaine 0.1% is the first listed.
NCT01898689 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01898689 about?
NCT01898689 is a clinical study titled "Optimizing Local Anesthetic Concentration for Continuous Popliteal-Sciatic Nerve Blocks". A continuous peripheral nerve block-also termed "perineural local anesthetic infusion"-involves the insertion of a tiny tube (a "catheter") through the skin and adjacent to a peripheral nerve, followed by local anesthetic (numbing medicine) administration via the catheter, providing pain control fol...
What is the current status of trial NCT01898689?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 24 participants. The study started on 2013-07. Estimated completion is 2013-11.
What interventions are being tested in trial NCT01898689?
The interventions under investigation include: Ropivacaine 0.1% (DRUG), Ropivacaine 0.4% (DRUG).
Who is sponsoring clinical trial NCT01898689?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
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