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NCT01882231 · ClinicalTrials.gov registry record · NA
Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing Sarcoma
A NA study, sponsored by Vanderbilt-Ingram Cancer Center.
- Terminated
- Registry status
- NA
- Development phase
- 6
- Enrollment target
NCT01882231: Clinical Trial NA study, sponsored by Vanderbilt-Ingram Cancer Center.
NCT01882231 is a NA study that was terminated before completion, run by Vanderbilt-Ingram Cancer Center. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01882231, a NA study, was terminated before completion, sponsored by Vanderbilt-Ingram Cancer Center.
- TERMINATED
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
Study Summary
The objective of these studies is to use changes in 3 Tesla MRI measurements of tumor protein content, cell density, and microvessel perfusion, obtained before and after a single cycle of NAC, to predict eventual tumor response observed at the conclusion of NAC, within patients with osteosarcoma or Ewing Sarcoma.
Primary Outcome
Use 3T CEST-MRI, DW-MRI, and DCE-MRI to quantitatively measure protein content (APTasym), tumor cellularity (ADC), and tumor perfusion (Ktrans)and measure changes in these parameters from baseline to post 1 cycle of neoadjuvant chemotherapy.
Interventions
- OTHER DCE-MRI, DW-MRI, MT-MRI, and CEST-MRI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2013-03 |
| Est. Completion | 2016-04-25 |
| Phase | NA |
Why NCT01882231 stopped before completion
NCT01882231 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which DCE-MRI, DW-MRI, MT-MRI, and CEST-MRI is the first listed.
NCT01882231 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01882231 about?
NCT01882231 is a clinical study titled "Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing Sarcoma". The objective of these studies is to use changes in 3 Tesla MRI measurements of tumor protein content, cell density, and microvessel perfusion, obtained before and after a single cycle of NAC, to predict eventual tumor response observed at the conclusion of NAC, within patients with osteosarcoma or ...
What is the current status of trial NCT01882231?
This trial is currently terminated. It is a NA study. The enrollment target is 6 participants. The study started on 2013-03. Estimated completion is 2016-04-25.
What interventions are being tested in trial NCT01882231?
The interventions under investigation include: DCE-MRI, DW-MRI, MT-MRI, and CEST-MRI (OTHER).
Who is sponsoring clinical trial NCT01882231?
This trial is sponsored by Vanderbilt-Ingram Cancer Center, which has 189 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01882231's enrollment target sits among peer trials
6 1983rd of 2000 higher than 13 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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