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NCT01880749 · ClinicalTrials.gov registry record · Early Phase 1

Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas

A Early Phase 1 study, sponsored by NYU Langone Health.

Completed
Registry status
Early Phase 1
Development phase
5
Enrollment target

NCT01880749 is a Early Phase 1 study that has completed, run by NYU Langone Health. The registered enrollment target is 5 participants.

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The verdict

NCT01880749, a Early Phase 1 study, has completed, sponsored by NYU Langone Health.

COMPLETED
Registry status
Early Phase 1
Development phase
5 participants
Enrollment target

Study Summary

The primary objective is to estimate the proportions of vestibular schwannomas (VS) and meningiomas after 10 days of exposure to the study drug RAD001 at a dose of 10 mg daily, as determined by immunohistochemistry. This is a "phase 0" PK (pharmacokinetic) and PD (pharmacodynamic) study of RAD001 in patients with Neurofibromatosis Type 2-related and sporadic VS and meningiomas. Enrolled patients will take RAD001 prior to a scheduled VS or meningioma surgery, and blood and tissue samples will be obtained for further analysis.

Interventions

  • DRUG RAD001

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2013-06
Est. Completion 2019-12
Phase Early Phase 1

Sponsor

NYU Langone Health

1,164 total trials

What the Registry Record Tells You About NCT01880749

The ClinicalTrials.gov registry entry for NCT01880749 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NYU Langone Health, which has 1,164 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which RAD001 is the first listed.

NCT01880749 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01880749 about?

NCT01880749 is a clinical study titled "Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas". The primary objective is to estimate the proportions of vestibular schwannomas (VS) and meningiomas after 10 days of exposure to the study drug RAD001 at a dose of 10 mg daily, as determined by immunohistochemistry. This is a "phase 0" PK (pharmacokinetic) and PD (pharmacodynamic) study of RAD001 in...

What is the current status of trial NCT01880749?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 5 participants. The study started on 2013-06. Estimated completion is 2019-12.

What interventions are being tested in trial NCT01880749?

The interventions under investigation include: RAD001 (DRUG).

Who is sponsoring clinical trial NCT01880749?

This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.