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NCT01875848 · ClinicalTrials.gov registry record · Phase 4
Buprenorphine vs. Opioid Dose Escalation Among Patients With Chronic Pain
A Phase 4 study, sponsored by VA Office of Research and Development.
- Terminated
- Registry status
- Phase 4
- Development phase
- 7
- Enrollment target
NCT01875848: Clinical Trial Phase 4 study, sponsored by VA Office of Research and Development.
NCT01875848 is a Phase 4 study that was terminated before completion, run by VA Office of Research and Development. The registered enrollment target is 7 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01875848, a Phase 4 study, was terminated before completion, sponsored by VA Office of Research and Development.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 7 participants
- Enrollment target
Study Summary
This study compares buprenorphine/naloxone to opioid dose escalation among patients with poorly controlled non-cancer pain on 30-100 mg daily morphine equivalent opioid dose.
Primary Outcome
Validated 11 pt scale 0-10, to evaluate a patient's current severity of pain. A rating of 0 indicates no pain while 10 indicates the worst pain imaginable. A score of 4 or above is considered a clinically significant pain level according to VHA treatment guidelines.
Interventions
- DRUG buprenorphine/naloxone
- DRUG opioid dose escalation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2013-12 |
| Est. Completion | 2015-06 |
| Phase | Phase 4 |
Why NCT01875848 stopped before completion
NCT01875848 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which buprenorphine/naloxone is the first listed.
NCT01875848 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01875848 about?
NCT01875848 is a clinical study titled "Buprenorphine vs. Opioid Dose Escalation Among Patients With Chronic Pain". This study compares buprenorphine/naloxone to opioid dose escalation among patients with poorly controlled non-cancer pain on 30-100 mg daily morphine equivalent opioid dose.
What is the current status of trial NCT01875848?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 7 participants. The study started on 2013-12. Estimated completion is 2015-06.
What interventions are being tested in trial NCT01875848?
The interventions under investigation include: buprenorphine/naloxone (DRUG), opioid dose escalation (DRUG).
Who is sponsoring clinical trial NCT01875848?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01875848's enrollment target sits among peer trials
7 1981st of 2000 higher than 18 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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