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NCT01870427 · ClinicalTrials.gov registry record · Phase 4

NEWTON: Aflibercept Injection for Previously Treated Macular Edema Associated With Central Retinal Vein Occlusions

A Phase 4 study, sponsored by Northern California Retina Vitreous Associates.

Completed
Registry status
Phase 4
Development phase
20
Enrollment target

NCT01870427: Completed Phase 4 study, sponsored by Northern California Retina Vitreous Associates.

NCT01870427 is a Phase 4 study that has completed, run by Northern California Retina Vitreous Associates. The registered enrollment target is 20 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01870427, a Phase 4 study, has completed, sponsored by Northern California Retina Vitreous Associates.

COMPLETED
Registry status
Phase 4
Development phase
20 participants
Enrollment target

Study Summary

The purpose of the study is to determine the effect of Intravitreal Aflibercept Injection (IAI) on previously treated Central Retinal Vein Occlusions (CRVOs) with other Anti-VEGF agents.

Primary Outcome

Mean number of weeks between each injection where there is no macular edema

Interventions

  • DRUG Aflibercept (2.0 mg)

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2013-06
Est. Completion 2016-08
Phase Phase 4

What the finished NCT01870427 record still lists

NCT01870427 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 1 intervention - of which Aflibercept (2.0 mg) is the first listed.

NCT01870427 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01870427 about?

NCT01870427 is a clinical study titled "NEWTON: Aflibercept Injection for Previously Treated Macular Edema Associated With Central Retinal Vein Occlusions". The purpose of the study is to determine the effect of Intravitreal Aflibercept Injection (IAI) on previously treated Central Retinal Vein Occlusions (CRVOs) with other Anti-VEGF agents.

What is the current status of trial NCT01870427?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2013-06. Estimated completion is 2016-08.

What interventions are being tested in trial NCT01870427?

The interventions under investigation include: Aflibercept (2.0 mg) (DRUG).

Who is sponsoring clinical trial NCT01870427?

This trial is sponsored by Northern California Retina Vitreous Associates, which has 4 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01870427's enrollment target sits among peer trials

20 1753rd of 2000 higher than 167 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01870427, the US trial registry maintained by the National Library of Medicine. NCT01870427 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.