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NCT01864200 · ClinicalTrials.gov registry record · Phase 4

Randomized, Double-Blind, Placebo-Controlled Study: CroFab® vs Placebo for Copperhead Snake Envenomation

A Phase 4 study of Snake Bites, sponsored by BTG International.

Completed
Registry status
Phase 4
Development phase
74
Enrollment target
18
Study locations

NCT01864200 is a Phase 4 study of Snake Bites that has completed, run by BTG International. The registered enrollment target is 74 participants. The trial reports 18 study locations across 9 states.

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The verdict

NCT01864200, a Phase 4 study of Snake Bites, has completed, sponsored by BTG International.

COMPLETED
Registry status
Phase 4
Development phase
74 participants
Enrollment target
18
Study locations

Study Summary

This study will evaluate the recovery from copperhead snake bite in patients with mild or moderate venom effect. Potential subjects received CroFab antivenom or placebo. After blinded treatment and discharge, the subject returns to the clinic for follow-up assessments at day 3, 7, 14, and 28 after snake bite as well as follow-up telephone assessments on day 10, 17, and 24 after snake bite. The purpose of this study is to compare recovery in copperhead snake bite patients treated with antivenom vs placebo (no active drug) as measured by the Patient Specific Functional Scale (PSFS) at Day 14 follow-up. The primary efficacy endpoint of this study was achieved.

Conditions Studied

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL Crotalidae polyvalent immune fab (ovine)

Study Locations (18)

Texas

  • St Joseph Regional Health Center - Bryan
  • University of Texas - Southwestern - Dallas
  • Ben Taub General Hospital - Houston
  • Texas Children's Hospital - Houston
  • Scott & White Hospital - Temple

North Carolina

  • University of North Carolina - Chapel Hill
  • Duke University - Durham
  • Vidant Medical Center - Greenville

Pennsylvania

  • Lehigh Valley Hospital Center - Allentown
  • University of Pittsburgh - Pittsburgh

South Carolina

  • Medical University of South Carolina - Charleston
  • Palmetto Health Richland - Columbia

Virginia

  • University of Virginia - Charlottesville
  • Virginia Commonwealth University - Richmond

Georgia

  • Georgia Regents University - Augusta

Kansas

  • University of Kansas Hospital - Kansas City

Missouri

  • Washington University - St Louis

Trial Details

FieldValue
Enrollment Target 74 participants
Start Date 2013-07
Est. Completion 2015-12
Phase Phase 4

Sponsor

BTG International

5 total trials

What the Registry Record Tells You About NCT01864200

The ClinicalTrials.gov registry entry for NCT01864200 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 74 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is BTG International, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Snake Bites appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT01864200 reports 18 study locations spanning 9 distinct geographic areas - top geographies include Texas, North Carolina, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT01864200 about?

NCT01864200 is a clinical study titled "Randomized, Double-Blind, Placebo-Controlled Study: CroFab® vs Placebo for Copperhead Snake Envenomation". This study will evaluate the recovery from copperhead snake bite in patients with mild or moderate venom effect. Potential subjects received CroFab antivenom or placebo. After blinded treatment and discharge, the subject returns to the clinic for follow-up assessments at day 3, 7, 14, and 28 after s...

What is the current status of trial NCT01864200?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 74 participants. The study started on 2013-07. Estimated completion is 2015-12.

What conditions does trial NCT01864200 study?

This clinical trial studies the following conditions: Snake Bites.

What interventions are being tested in trial NCT01864200?

The interventions under investigation include: Placebo (BIOLOGICAL), Crotalidae polyvalent immune fab (ovine) (BIOLOGICAL).

Who is sponsoring clinical trial NCT01864200?

This trial is sponsored by BTG International, which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01864200 being conducted?

This trial has 18 study locations across Georgia, Kansas, Missouri, North Carolina, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.