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NCT01862705 · ClinicalTrials.gov registry record · NA
Using fMRI to Determine if Cerebral Hemodynamic Responses to Pain Change Following Thoracic Spine Manipulation in Individuals With Mechanical Neck Pain
A NA study, sponsored by OSF Healthcare System.
- Completed
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT01862705 is a NA study that has completed, run by OSF Healthcare System. The registered enrollment target is 24 participants.
The verdict
NCT01862705, a NA study, has completed, sponsored by OSF Healthcare System.
- COMPLETED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
Thoracic spine thrust manipulation (TSM) has been shown to be an effective intervention in the management of patients with neck pain. However the mechanisms for pain relief associated with this intervention remain largely unexplained. Recent evidence suggests structures within the brain may have a role in creating responses of pain relief. This study aims to use functional magnetic resonance imaging (fMRI) to determine if there is a change in blood flow to structures within the brain following TSM in patients with neck pain. All patients will undergo fMRI while receiving painful stimuli directed to two separate sites, the cuticle of the index finger and the great toe. Subjects will then receive either TSM or sham-manipulation and then immediately undergo a second fMRI scan receiving the same painful stimuli. The primary outcome of interest is the shift in blood flow within the brain before and after TSM or sham manipulation as measured by Blood Oxygen Level Dependent (BOLD) technology. This study will be the first to examine this type of response to manual therapy within the brain in patients with neck pain.
Interventions
- OTHER Thoracic spine manipulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2013-05 |
| Est. Completion | 2014-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01862705
The ClinicalTrials.gov registry entry for NCT01862705 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is OSF Healthcare System, which has 14 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Thoracic spine manipulation is the first listed.
NCT01862705 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01862705 about?
NCT01862705 is a clinical study titled "Using fMRI to Determine if Cerebral Hemodynamic Responses to Pain Change Following Thoracic Spine Manipulation in Individuals With Mechanical Neck Pain". Thoracic spine thrust manipulation (TSM) has been shown to be an effective intervention in the management of patients with neck pain. However the mechanisms for pain relief associated with this intervention remain largely unexplained. Recent evidence suggests structures within the brain may have a r...
What is the current status of trial NCT01862705?
This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2013-05. Estimated completion is 2014-10.
What interventions are being tested in trial NCT01862705?
The interventions under investigation include: Thoracic spine manipulation (OTHER).
Who is sponsoring clinical trial NCT01862705?
This trial is sponsored by OSF Healthcare System, which has 14 total clinical trials registered on ClinicalTrials.gov.
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