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NCT01856361 · ClinicalTrials.gov registry record · NA

Ramipril for the Treatment of Oligospermia

A NA study, sponsored by Weill Medical College of Cornell University.

Terminated
Registry status
NA
Development phase
2
Enrollment target

NCT01856361: Clinical Trial NA study, sponsored by Weill Medical College of Cornell University.

NCT01856361 is a NA study that was terminated before completion, run by Weill Medical College of Cornell University. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01856361, a NA study, was terminated before completion, sponsored by Weill Medical College of Cornell University.

TERMINATED
Registry status
NA
Development phase
2 participants
Enrollment target

Study Summary

This is a randomized controlled trial to evaluate the effect of ramipril in stimulating and promoting sperm production in men with low sperm count. Ramipril is an Angiotensin Converting Enzyme Inhibitor (ACEI) currently used to treat high blood pressure. However, previous studies have shown that this class of medications can improve sperm parameters. The purpose of this study is to evaluate the efficacy of ramipril compared to placebo (Substance That is not known to have treatment effect), in improving sperm density in infertile men with documented low sperm count. This study will help us identify subjects that might benefit from treatment with this medication, and the effect it will have on sperm count, shape, and motility.

Interventions

  • DRUG Placebo
  • DRUG Ramipril

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2013-07
Est. Completion 2016-06
Phase NA

Why NCT01856361 stopped before completion

NCT01856361 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01856361 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01856361 about?

NCT01856361 is a clinical study titled "Ramipril for the Treatment of Oligospermia". This is a randomized controlled trial to evaluate the effect of ramipril in stimulating and promoting sperm production in men with low sperm count. Ramipril is an Angiotensin Converting Enzyme Inhibitor (ACEI) currently used to treat high blood pressure. However, previous studies have shown that thi...

What is the current status of trial NCT01856361?

This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2013-07. Estimated completion is 2016-06.

What interventions are being tested in trial NCT01856361?

The interventions under investigation include: Placebo (DRUG), Ramipril (DRUG).

Who is sponsoring clinical trial NCT01856361?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01856361's enrollment target sits among peer trials

2 1997th of 2000 the lowest of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01856361, the US trial registry maintained by the National Library of Medicine. NCT01856361 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.