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NCT01856036 · ClinicalTrials.gov registry record · NA
Anti-Tumor Immunity Induced by Cryoablation of Invasive Breast Cancers
A NA study, sponsored by Saint John's Cancer Institute.
- Terminated
- Registry status
- NA
- Development phase
- 2
- Enrollment target
NCT01856036: Clinical Trial NA study, sponsored by Saint John's Cancer Institute.
NCT01856036 is a NA study that was terminated before completion, run by Saint John's Cancer Institute. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01856036, a NA study, was terminated before completion, sponsored by Saint John's Cancer Institute.
- TERMINATED
- Registry status
- NA
- Development phase
- 2 participants
- Enrollment target
Study Summary
This protocol will study the impact of cryoablation on immune response in patients diagnosed with invasive breast cancers smaller than 1.5 cm. It will profile the immune response to cryoablation of invasive breast cancers. The intra-tumoral and systemic immune response to cryoablation will be determined and compared to pre-ablated breast cancer specimens and historical control specimens.
Primary Outcome
1. Determine number (percentage via flow cytometry), phenotype and functionality of tumor infiltrating lymphocytes in ablated breast cancer 2. Determine number (percentage via flow cytometry)and phenotype of APC in ablated breast cancer 3. Characterize cytokine and chemokine expression (in IU) in ablated tissue and in pre-ablated and post-ablated serum over time 4. Quantify T cell response (IUs of IL2 and IFN gamma, and T cell specific cells as measured by number of spots on an elispot assay) to
Interventions
- PROCEDURE Cryoablation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2013-04 |
| Est. Completion | 2014-10 |
| Phase | NA |
Why NCT01856036 stopped before completion
NCT01856036 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Cryoablation is the first listed.
NCT01856036 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01856036 about?
NCT01856036 is a clinical study titled "Anti-Tumor Immunity Induced by Cryoablation of Invasive Breast Cancers". This protocol will study the impact of cryoablation on immune response in patients diagnosed with invasive breast cancers smaller than 1.5 cm. It will profile the immune response to cryoablation of invasive breast cancers. The intra-tumoral and systemic immune response to cryoablation will be determ...
What is the current status of trial NCT01856036?
This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2013-04. Estimated completion is 2014-10.
What interventions are being tested in trial NCT01856036?
The interventions under investigation include: Cryoablation (PROCEDURE).
Who is sponsoring clinical trial NCT01856036?
This trial is sponsored by Saint John's Cancer Institute, which has 19 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01856036's enrollment target sits among peer trials
2 1997th of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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