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NCT01852175 · ClinicalTrials.gov registry record · NA

Pharmacodynamic Effects of Prasugrel Compared With Ticagrelor in Patients With Coronary Artery Disease

A NA study, sponsored by University of Florida.

Completed
Registry status
NA
Development phase
110
Enrollment target

NCT01852175: Completed NA study, sponsored by University of Florida.

NCT01852175 is a NA study that has completed, run by University of Florida. The registered enrollment target is 110 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01852175, a NA study, has completed, sponsored by University of Florida.

COMPLETED
Registry status
NA
Development phase
110 participants
Enrollment target

Study Summary

Recently, two P2Y12 receptor inhibitors have been approved for clinical use: prasugrel and ticagrelor. Both prasugrel and ticagrelor have shown to be associated with more potent antiplatelet effects compared with clopidogrel and are associated with an improved net clinical benefit. However, to date there are limited head-to-head comparisons of these two new agents.

Primary Outcome

The primary end-point of the study was the comparison in the platelet reactivity index (PRI%) determined by vasodilator-stimulated phosphoprotein (VASP) at 1 week between prasugrel and ticagrelor.

Interventions

  • DRUG Prasugrel
  • DRUG Ticagrelor

Trial Details

FieldValue
Enrollment Target 110 participants
Start Date 2012-01
Est. Completion 2014-07
Phase NA
University of Florida

1,106 total trials

What the finished NCT01852175 record still lists

NCT01852175 is an interventional study that assigns participants to a tested intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 2 interventions - of which Prasugrel is the first listed.

NCT01852175 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01852175 about?

NCT01852175 is a clinical study titled "Pharmacodynamic Effects of Prasugrel Compared With Ticagrelor in Patients With Coronary Artery Disease". Recently, two P2Y12 receptor inhibitors have been approved for clinical use: prasugrel and ticagrelor. Both prasugrel and ticagrelor have shown to be associated with more potent antiplatelet effects compared with clopidogrel and are associated with an improved net clinical benefit. However, to date ...

What is the current status of trial NCT01852175?

This trial is currently completed. It is a NA study. The enrollment target is 110 participants. The study started on 2012-01. Estimated completion is 2014-07.

What interventions are being tested in trial NCT01852175?

The interventions under investigation include: Prasugrel (DRUG), Ticagrelor (DRUG).

Who is sponsoring clinical trial NCT01852175?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01852175's enrollment target sits among peer trials

110 816th of 2000 higher than 1,176 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01852175, the US trial registry maintained by the National Library of Medicine. NCT01852175 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.