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NCT01849744 · ClinicalTrials.gov registry record · Phase 1
Phase I Dose Escalation Study of VS-4718 in Subjects With Metastatic Non-Hematologic Malignancies
A Phase 1 study, sponsored by Verastem.
- Terminated
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT01849744 is a Phase 1 study that was terminated before completion, run by Verastem. The registered enrollment target is 48 participants.
The verdict
NCT01849744, a Phase 1 study, was terminated before completion, sponsored by Verastem.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
This is a Phase I, open-label, multicenter, dose-escalation trial of VS-4718, a focal adhesion kinase inhibitor, in subjects with metastatic non-hematologic malignancies. This clinical study is comprised of 2 parts: Part 1 (Dose Escalation) and Part 2 (Expansion). The purpose of this study is to evaluate the safety (including the recommended Phase II dose), pharmacokinetics (the amount of VS-4718 in your blood) and the anti-cancer activity of VS-4718. The pharmacodynamic effects (genes or proteins that may predict or show how your body may respond to VS-4718) will also be examined in tumor biopsies and blood samples.
Interventions
- DRUG VS-4718
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2013-06 |
| Est. Completion | 2017-06 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01849744
The ClinicalTrials.gov registry entry for NCT01849744 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Verastem, which has 21 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which VS-4718 is the first listed.
NCT01849744 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01849744 about?
NCT01849744 is a clinical study titled "Phase I Dose Escalation Study of VS-4718 in Subjects With Metastatic Non-Hematologic Malignancies". This is a Phase I, open-label, multicenter, dose-escalation trial of VS-4718, a focal adhesion kinase inhibitor, in subjects with metastatic non-hematologic malignancies. This clinical study is comprised of 2 parts: Part 1 (Dose Escalation) and Part 2 (Expansion). The purpose of this study is to eva...
What is the current status of trial NCT01849744?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2013-06. Estimated completion is 2017-06.
What interventions are being tested in trial NCT01849744?
The interventions under investigation include: VS-4718 (DRUG).
Who is sponsoring clinical trial NCT01849744?
This trial is sponsored by Verastem, which has 21 total clinical trials registered on ClinicalTrials.gov.
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