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NCT01848327 · ClinicalTrials.gov registry record · NA

Caprylic Triglyceride for Treatment of Cognitive Impairments in Multiple Sclerosis

A NA study, sponsored by University of Miami.

Completed
Registry status
NA
Development phase
124
Enrollment target

NCT01848327: Completed NA study, sponsored by University of Miami.

NCT01848327 is a NA study that has completed, run by University of Miami. The registered enrollment target is 124 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01848327, a NA study, has completed, sponsored by University of Miami.

COMPLETED
Registry status
NA
Development phase
124 participants
Enrollment target

Study Summary

Background/Rationale: Cognitive problems are a common symptom in individuals with Multiple Sclerosis (MS). Treatment options are limited, and there is a pressing need for new interventions to treat MS-related cognitive impairment. Glucose (a type of sugar) is used to fuel the cells of the healthy brain. For people with neurological conditions such as MS, glucose is not converted into energy as efficiently as it would be in a healthy brain, which can lead to a decrease in cognitive function. Caprylic Triglyceride may work to bypass this problem by providing an alternative energy source that is metabolized in the liver and used by the brain. Objective: To evaluate the therapeutic effects of 90 days of caprylic triglyceride on cognitive impairment in multiple sclerosis. Design: Randomized, double blinded, placebo controlled trial of 158 subjects. Outcome: Change in Total Learning (Trials 1-5) on the California Verbal Learning Test-2nd Edition-(CVLT-II) AND Change in Symbol Digit Modalities Test (SDMT) (at day 90

Primary Outcome

measure of verbal learning and memory

Interventions

  • DIETARY_SUPPLEMENT Placebo
  • DIETARY_SUPPLEMENT Caprylic Triglyceride

Trial Details

FieldValue
Enrollment Target 124 participants
Start Date 2013-02
Est. Completion 2017-12
Phase NA
University of Miami

721 total trials

What the finished NCT01848327 record still lists

NCT01848327 is an interventional study that assigns participants to a tested intervention. The registered 124 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01848327 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01848327 about?

NCT01848327 is a clinical study titled "Caprylic Triglyceride for Treatment of Cognitive Impairments in Multiple Sclerosis". Background/Rationale: Cognitive problems are a common symptom in individuals with Multiple Sclerosis (MS). Treatment options are limited, and there is a pressing need for new interventions to treat MS-related cognitive impairment. Glucose (a type of sugar) is used to fuel the cells of the healthy br...

What is the current status of trial NCT01848327?

This trial is currently completed. It is a NA study. The enrollment target is 124 participants. The study started on 2013-02. Estimated completion is 2017-12.

What interventions are being tested in trial NCT01848327?

The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Caprylic Triglyceride (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT01848327?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01848327's enrollment target sits among peer trials

124 758th of 2000 higher than 1,239 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01848327, the US trial registry maintained by the National Library of Medicine. NCT01848327 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.