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NCT01846728 · ClinicalTrials.gov registry record · NA
Effects of Estrogen Deficiency on Energy Expenditure
A NA study, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- NA
- Development phase
- 6
- Enrollment target
NCT01846728: Completed NA study, sponsored by University of Colorado, Denver.
NCT01846728 is a NA study that has completed, run by University of Colorado, Denver. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01846728, a NA study, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
Study Summary
Menopause is associated with weight gain, but the reasons why are not clear. In this study, the investigators will determine if reducing estrogen levels causes a decrease in the ability of the body to produce heat. If so, this would suggest this is one way that menopause may cause weight gain.
Primary Outcome
Brown adipose tissue activity will be measured using Positron Emission Tomography/computer tomography (PET/CT) before and after 3 months of estrogen suppression. Activity is quantified as the standard uptake value (SUV), It is a mathematically derived ratio that is a semiquantitative measure of the tracer uptake in a region of interest that normalizes the lesion activity to the injected activity and a measure of the volume of distribution (usually total body weight or lean body mass).
Interventions
- DRUG Estrogen suppression
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2013-04 |
| Est. Completion | 2016-10 |
| Phase | NA |
What the finished NCT01846728 record still lists
NCT01846728 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Estrogen suppression is the first listed.
NCT01846728 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01846728 about?
NCT01846728 is a clinical study titled "Effects of Estrogen Deficiency on Energy Expenditure". Menopause is associated with weight gain, but the reasons why are not clear. In this study, the investigators will determine if reducing estrogen levels causes a decrease in the ability of the body to produce heat. If so, this would suggest this is one way that menopause may cause weight gain.
What is the current status of trial NCT01846728?
This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2013-04. Estimated completion is 2016-10.
What interventions are being tested in trial NCT01846728?
The interventions under investigation include: Estrogen suppression (DRUG).
Who is sponsoring clinical trial NCT01846728?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01846728's enrollment target sits among peer trials
6 1983rd of 2000 higher than 13 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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