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NCT01846364 · ClinicalTrials.gov registry record · Early Phase 1
DIM as a Treatment for Thyroid Disease
A Early Phase 1 study, sponsored by The New York Eye & Ear Infirmary.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 7
- Enrollment target
NCT01846364: Clinical Trial Early Phase 1 study, sponsored by The New York Eye & Ear Infirmary.
NCT01846364 is a Early Phase 1 study that was terminated before completion, run by The New York Eye & Ear Infirmary. The registered enrollment target is 7 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01846364, a Early Phase 1 study, was terminated before completion, sponsored by The New York Eye & Ear Infirmary.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
Diindolylmethane (DIM), a dietary supplement, found naturally in cruciferous vegetables (such as cabbage, cauliflower, broccoli, \& Brussels sprouts) has been studied extensively in recent years for its anti-cancer effects. DIM has been shown to exert control over cancer cell growth in breast, uterine, cervical, ovarian, and colon cancer. To date no human study has been published regarding the bioavailability of DIM in thyroid tissue or its effects in proliferative thyroid disease. Our previous study attempted to elucidate DIM's promotion of anti-proliferative estrogen metabolites in proliferative thyroid disease and ascertain its uptake in thyroid tissue. DIM has been shown to concentrate in the thyroid gland. Furthermore, thyroid volumes have been seen to decrease subjectively. This study would continue our attempt to elucidate DIM's promotion of anti-proliferative estrogen metabolites in proliferative thyroid disease.
Interventions
- DIETARY_SUPPLEMENT Diindolylmethane (DIM)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2006-11 |
| Est. Completion | 2011-09 |
| Phase | Early Phase 1 |
Why NCT01846364 stopped before completion
NCT01846364 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 1 intervention - of which Diindolylmethane (DIM) is the first listed.
NCT01846364 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01846364 about?
NCT01846364 is a clinical study titled "DIM as a Treatment for Thyroid Disease". Diindolylmethane (DIM), a dietary supplement, found naturally in cruciferous vegetables (such as cabbage, cauliflower, broccoli, \& Brussels sprouts) has been studied extensively in recent years for its anti-cancer effects. DIM has been shown to exert control over cancer cell growth in breast, uteri...
What is the current status of trial NCT01846364?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 7 participants. The study started on 2006-11. Estimated completion is 2011-09.
What interventions are being tested in trial NCT01846364?
The interventions under investigation include: Diindolylmethane (DIM) (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01846364?
This trial is sponsored by The New York Eye & Ear Infirmary, which has 12 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01846364's enrollment target sits among peer trials
7 1825th of 2000 higher than 156 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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