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NCT01845441 · ClinicalTrials.gov registry record · Phase 2
Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions
A Phase 2 study, sponsored by University Hospitals Cleveland Medical Center.
- Terminated
- Registry status
- Phase 2
- Development phase
- 7
- Enrollment target
NCT01845441: Clinical Trial Phase 2 study, sponsored by University Hospitals Cleveland Medical Center.
NCT01845441 is a Phase 2 study that was terminated before completion, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 7 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01845441, a Phase 2 study, was terminated before completion, sponsored by University Hospitals Cleveland Medical Center.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 7 participants
- Enrollment target
Study Summary
Dexmedetomidine is a unique sedative medication able to provide sedation without causing respiratory depression and maintaining neurological functions. Patients having an acute ischemic stroke and need to undergo endovascular therapy require constant assessment of their neurological status prior, during and after the interventional procedure. In this study the investigators will compare the efficacy of Dexmedetomidine to other standard sedative medications in providing optimal sedative effect while maintaining neurological function.
Primary Outcome
Patient will be continuously monitored for movements that delays or adversely affect the performance of the procedure by the patient assessor in a safe and timely manner (an event). One minute interval between patient event assessments will be given to prevent subjective bias. After every one minute, it will be determined if an event has occurred. Over the length of the procedure, the total number of one-minute intervals with an event occurrence will be summed and then divided by the total of mi
Interventions
- DRUG Midazolam
- DRUG Dexmedetomidine
- DRUG Fentanyl
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2012-04 |
| Est. Completion | 2021-12 |
| Phase | Phase 2 |
Why NCT01845441 stopped before completion
NCT01845441 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 3 interventions - of which Midazolam is the first listed.
NCT01845441 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01845441 about?
NCT01845441 is a clinical study titled "Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions". Dexmedetomidine is a unique sedative medication able to provide sedation without causing respiratory depression and maintaining neurological functions. Patients having an acute ischemic stroke and need to undergo endovascular therapy require constant assessment of their neurological status prior, du...
What is the current status of trial NCT01845441?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 7 participants. The study started on 2012-04. Estimated completion is 2021-12.
What interventions are being tested in trial NCT01845441?
The interventions under investigation include: Midazolam (DRUG), Dexmedetomidine (DRUG), Fentanyl (DRUG).
Who is sponsoring clinical trial NCT01845441?
This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01845441's enrollment target sits among peer trials
7 1996th of 2000 higher than 5 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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