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NCT01844739 · ClinicalTrials.gov registry record · Phase 1

A Phase 1 Study Evaluating Safety and Tolerability of NVN1000 Gel

A Phase 1 study, sponsored by Novan.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target

NCT01844739: Completed Phase 1 study, sponsored by Novan.

NCT01844739 is a Phase 1 study that has completed, run by Novan. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01844739, a Phase 1 study, has completed, sponsored by Novan.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

This is a 2 week Phase 1 study of SB204 (NVN1000 Gel) in healthy adult volunteers with elevated Propionibacterium acnes (P. acnes) counts. Subjects will apply NVN1000 4% Gel or Vehicle Gel twice daily to their face. Assessments will include cutaneous tolerability, safety, and P. acnes counts.

Primary Outcome

Cutaneous tolerability assessments (erythema, scaling, dryness, pruritus, burning/stinging) will be summarized with frequency counts and percentages at each score category for Week 1 and Week 2.

Interventions

  • DRUG Vehicle Gel
  • DRUG NVN1000 4% Gel

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2013-04
Est. Completion 2013-06
Phase Phase 1
Novan

18 total trials

What the finished NCT01844739 record still lists

NCT01844739 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 2 interventions - of which Vehicle Gel is the first listed.

NCT01844739 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01844739 about?

NCT01844739 is a clinical study titled "A Phase 1 Study Evaluating Safety and Tolerability of NVN1000 Gel". This is a 2 week Phase 1 study of SB204 (NVN1000 Gel) in healthy adult volunteers with elevated Propionibacterium acnes (P. acnes) counts. Subjects will apply NVN1000 4% Gel or Vehicle Gel twice daily to their face. Assessments will include cutaneous tolerability, safety, and P. acnes counts.

What is the current status of trial NCT01844739?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2013-04. Estimated completion is 2013-06.

What interventions are being tested in trial NCT01844739?

The interventions under investigation include: Vehicle Gel (DRUG), NVN1000 4% Gel (DRUG).

Who is sponsoring clinical trial NCT01844739?

This trial is sponsored by Novan, which has 18 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01844739's enrollment target sits among peer trials

30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01844739, the US trial registry maintained by the National Library of Medicine. NCT01844739 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.