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NCT01844401 · ClinicalTrials.gov registry record · Phase 1

Pharmacokinetic and Pharmacodynamic Profiles of Albuterol Spiromax® and ProAir® Hydrofluoroalkane (HFA) in Pediatric Patients With Asthma

A Phase 1 study, sponsored by Teva Branded Pharmaceutical Products R&D.

Completed
Registry status
Phase 1
Development phase
15
Enrollment target

NCT01844401: Completed Phase 1 study, sponsored by Teva Branded Pharmaceutical Products R&D.

NCT01844401 is a Phase 1 study that has completed, run by Teva Branded Pharmaceutical Products R&D. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01844401, a Phase 1 study, has completed, sponsored by Teva Branded Pharmaceutical Products R&D.

COMPLETED
Registry status
Phase 1
Development phase
15 participants
Enrollment target

Study Summary

The primary objective of this study is to compare the pharmacokinetic (PK) profiles of Albuterol Spiromax® and ProAir HFA after administration of a single inhaled dose of 180 mcg albuterol base from each product.

Primary Outcome

Blood samples for plasma albuterol concentration determination will be drawn 5 (±2) minutes prior to dosing and at 30 (±2), 60 (±5), 120 (±10), 360 (±10), and 600 (±10) minutes after the completion of dosing.

Interventions

  • DRUG Albuterol Spiromax®
  • DRUG ProAir® HFA

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2013-04
Est. Completion 2013-10
Phase Phase 1

What the finished NCT01844401 record still lists

NCT01844401 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).

The record links to 0 conditions, and to 2 interventions - of which Albuterol Spiromax® is the first listed.

NCT01844401 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01844401 about?

NCT01844401 is a clinical study titled "Pharmacokinetic and Pharmacodynamic Profiles of Albuterol Spiromax® and ProAir® Hydrofluoroalkane (HFA) in Pediatric Patients With Asthma". The primary objective of this study is to compare the pharmacokinetic (PK) profiles of Albuterol Spiromax® and ProAir HFA after administration of a single inhaled dose of 180 mcg albuterol base from each product.

What is the current status of trial NCT01844401?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2013-04. Estimated completion is 2013-10.

What interventions are being tested in trial NCT01844401?

The interventions under investigation include: Albuterol Spiromax® (DRUG), ProAir® HFA (DRUG).

Who is sponsoring clinical trial NCT01844401?

This trial is sponsored by Teva Branded Pharmaceutical Products R&D, which has 167 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01844401's enrollment target sits among peer trials

15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01844401, the US trial registry maintained by the National Library of Medicine. NCT01844401 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.