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NCT01841658 · ClinicalTrials.gov registry record · NA
Folic Acid Supplementation in Women of Child Bearing Age
A NA study, sponsored by University of Georgia.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT01841658: Completed NA study, sponsored by University of Georgia.
NCT01841658 is a NA study that has completed, run by University of Georgia. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01841658, a NA study, has completed, sponsored by University of Georgia.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
The objective of this study is to identify genes whose expression is potentially modifiable due to changes in folate intake and help delineate mechanisms accounting for the variability in individual response to folic acid supplementation. The study will be conducted in normal weight and obese women of childbearing age, supplemented for 8 weeks with 800 mcg/day folic acid. It is hypothesized that (1) a change in folate status, induced by the supplementation, will influence the DNA methylation of specific genes and (2) the DNA methylation response to folic acid supplementation may differ between the normal weight and the obese women of childbearing age.
Primary Outcome
Change in DNA methylation in response to 4 or 8 weeks supplementation with 800 mcg/day of folic acid will be determined in DNA isolated from specific white blood cell types. Microarray analysis will be used to assess changes in multiple methylation sites within regulatory pathways for folate metabolism and/or development. Each subject will serve as her own control.
Interventions
- DIETARY_SUPPLEMENT Folic acid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2013-04 |
| Est. Completion | 2016-06 |
| Phase | NA |
What the finished NCT01841658 record still lists
NCT01841658 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which Folic acid is the first listed.
NCT01841658 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01841658 about?
NCT01841658 is a clinical study titled "Folic Acid Supplementation in Women of Child Bearing Age". The objective of this study is to identify genes whose expression is potentially modifiable due to changes in folate intake and help delineate mechanisms accounting for the variability in individual response to folic acid supplementation. The study will be conducted in normal weight and obese women ...
What is the current status of trial NCT01841658?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2013-04. Estimated completion is 2016-06.
What interventions are being tested in trial NCT01841658?
The interventions under investigation include: Folic acid (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01841658?
This trial is sponsored by University of Georgia, which has 59 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01841658's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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