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NCT01839461 · ClinicalTrials.gov registry record
Pharmacogenetic Morphine Spine Study
A clinical trial, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- 137
- Enrollment target
NCT01839461: Completed study, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT01839461 is a clinical trial that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 137 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01839461 has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- 137 participants
- Enrollment target
Study Summary
The purpose of this research study is to identify factors and genes (the DNA material that determines the makeup of the human body) that may be associated with how children cope with pain and respond to pain medication. Morphine is a pain medication commonly prescribed after this surgery during the hospital stay. The investigators want to study factors that may be associated with morphine requirement after surgery and side-effects from morphine. They will use pharmacometric models to identify dosing guidelines and factors associated with individual variability in metabolism and efficacy/safety of morphine. They will also study psychological, genetic and epigenetic factors associated with acute and chronic post-surgical pain after spine surgery. The investigators expect that the information obtained in this research study will help to develop effective, safer, and tailored treatment options in the future.
Primary Outcome
Pain score will be measured using standard and validated scales, Numeric rating scale (NRS 0 - 10). This scale has been widely validated and discriminates mild, moderate and severe pain
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 137 participants |
| Start Date | 2009-07 |
| Est. Completion | 2019-04-02 |
What the finished NCT01839461 record still lists
NCT01839461 is an observational study that tracks outcomes without assigning an intervention. The registered 137 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01839461 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01839461 about?
NCT01839461 is a clinical study titled "Pharmacogenetic Morphine Spine Study". The purpose of this research study is to identify factors and genes (the DNA material that determines the makeup of the human body) that may be associated with how children cope with pain and respond to pain medication. Morphine is a pain medication commonly prescribed after this surgery during the ...
What is the current status of trial NCT01839461?
This trial is currently completed. The enrollment target is 137 participants. The study started on 2009-07. Estimated completion is 2019-04-02.
Who is sponsoring clinical trial NCT01839461?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
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