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NCT01836809 · ClinicalTrials.gov registry record · Phase 4
Nesiritide and Renal Function After the Total Artificial Heart
A Phase 4 study, sponsored by Virginia Commonwealth University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 2
- Enrollment target
NCT01836809: Clinical Trial Phase 4 study, sponsored by Virginia Commonwealth University.
NCT01836809 is a Phase 4 study that was terminated before completion, run by Virginia Commonwealth University. The registered enrollment target is 2 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01836809, a Phase 4 study, was terminated before completion, sponsored by Virginia Commonwealth University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 2 participants
- Enrollment target
Study Summary
The prevalence of renal dysfunction after implantation of the artificial heart is high. The infusion of exogenous B-type natriuretic peptide (BNP) after implantation of the total artificial heart (TAH) improves renal function in a sustained manner. The renal protective and hormone-modulating effects of nesiritide may be enhanced with ventriculectomy compared to heart failure surgery that leaves the native myocardium intact. The goal of this project is to determine the renal protective effects of nesiritide after implantation of a mechanical device.
Interventions
- DRUG placebo
- DRUG nesiritide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2013-04 |
| Est. Completion | 2014-05 |
| Phase | Phase 4 |
Why NCT01836809 stopped before completion
NCT01836809 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.
NCT01836809 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01836809 about?
NCT01836809 is a clinical study titled "Nesiritide and Renal Function After the Total Artificial Heart". The prevalence of renal dysfunction after implantation of the artificial heart is high. The infusion of exogenous B-type natriuretic peptide (BNP) after implantation of the total artificial heart (TAH) improves renal function in a sustained manner. The renal protective and hormone-modulating effects...
What is the current status of trial NCT01836809?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 2 participants. The study started on 2013-04. Estimated completion is 2014-05.
What interventions are being tested in trial NCT01836809?
The interventions under investigation include: placebo (DRUG), nesiritide (DRUG).
Who is sponsoring clinical trial NCT01836809?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01836809's enrollment target sits among peer trials
2 1998th of 2000 higher than 1 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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