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NCT01835665 · ClinicalTrials.gov registry record · Phase 1

Dose Finding Study of Nimodipine for the Treatment of Progranulin Insufficiency From GRN Gene Mutations

A Phase 1 study, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 1
Development phase
8
Enrollment target

NCT01835665 is a Phase 1 study that has completed, run by University of California, San Francisco. The registered enrollment target is 8 participants.

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The verdict

NCT01835665, a Phase 1 study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 1
Development phase
8 participants
Enrollment target

Study Summary

The purpose of this study is to determine the maximum tolerated dose of nimodipine as well as the safety and tolerability of oral nimodipine in progranulin mutation carriers in preparation for longer term efficacy studies in patients with frontotemporal dementia due to progranulin gene mutations.

Interventions

  • DRUG Nimodipine

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2013-03
Est. Completion 2016-05
Phase Phase 1

What the Registry Record Tells You About NCT01835665

The ClinicalTrials.gov registry entry for NCT01835665 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Nimodipine is the first listed.

NCT01835665 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01835665 about?

NCT01835665 is a clinical study titled "Dose Finding Study of Nimodipine for the Treatment of Progranulin Insufficiency From GRN Gene Mutations". The purpose of this study is to determine the maximum tolerated dose of nimodipine as well as the safety and tolerability of oral nimodipine in progranulin mutation carriers in preparation for longer term efficacy studies in patients with frontotemporal dementia due to progranulin gene mutations.

What is the current status of trial NCT01835665?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2013-03. Estimated completion is 2016-05.

What interventions are being tested in trial NCT01835665?

The interventions under investigation include: Nimodipine (DRUG).

Who is sponsoring clinical trial NCT01835665?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.