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Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III
NCT01827046 · View on ClinicalTrials.gov ↗
Study Summary
A phase III, randomized, case-controlled, open-label, 500-subject clinical trial of minimally invasive surgery plus rt-PA in the treatment of intracerebral hemorrhage (ICH).
Conditions Studied
Interventions
- DRUG rt-PA
Study Locations (20)
Illinois
- Northwestern University — Chicago
- Rush University — Chicago
- University of Illinois at Chicago — Chicago
- University of Chicago Medical Center — Chicago
- Northshore University Health System, Evanston — Evanston
- Loyola University Chicago — Maywood
California
- Mercy San Juan Medical Center — Carmichael
- Scripps Health — La Jolla
- University of California, Los Angeles — Los Angeles
- University of California, San Diego — San Diego
- Stanford University — Stanford
Arizona
- Banner Good Samaritan Hospital — Phoenix
- Barrow Neurological Institute — Phoenix
Connecticut
- Hartford Hospital — Hartford
- Yale University — New Haven
Alabama
- University of Alabama at Birmingham — Birmingham
Florida
- Mayo Clinic, Jacksonville — Jacksonville
Georgia
- Gwinnett Medical Center — Lawrenceville
Kansas
- University of Kansas Medical Center — Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 499 participants |
| Start Date | 2013-12-30 |
| Est. Completion | 2018-09 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01827046
The ClinicalTrials.gov registry entry for NCT01827046 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 499 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,517 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Intracerebral Hemorrhage appearing as the primary indexed condition, and to 1 intervention — of which rt-PA is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01827046 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Illinois, California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01827046 about?
NCT01827046 is a clinical study titled "Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III". A phase III, randomized, case-controlled, open-label, 500-subject clinical trial of minimally invasive surgery plus rt-PA in the treatment of intracerebral hemorrhage (ICH).
What is the current status of trial NCT01827046?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 499 participants. The study started on 2013-12-30. Estimated completion is 2018-09.
What conditions does trial NCT01827046 study?
This clinical trial studies the following conditions: Intracerebral Hemorrhage. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT01827046?
The interventions under investigation include: rt-PA (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT01827046?
This trial is sponsored by Johns Hopkins University, which has 1,517 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01827046 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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