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NCT01826591 · ClinicalTrials.gov registry record · NA
DIETFITS Study (Diet Intervention Examining the Factors Interacting With Treatment Success
A NA study, sponsored by Stanford University.
- Completed
- Registry status
- NA
- Development phase
- 609
- Enrollment target
NCT01826591: Completed NA study, sponsored by Stanford University.
NCT01826591 is a NA study that has completed, run by Stanford University. The registered enrollment target is 609 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01826591, a NA study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- NA
- Development phase
- 609 participants
- Enrollment target
Study Summary
Genomics research is advancing rapidly, and links between genes and obesity continue to be discovered and better defined. A growing number of single nucleotide polymorphisms (SNPs) in multiple genes have been shown to alter an individual's response to dietary macronutrient composition. Based on prior genetic studies evaluating the body's physiological responses to dietary carbohydrates or fats, the investigators identified multi-locus genotype patterns with SNPs from three genes (FABP2, PPARG, and ADRB2): a low carbohydrate-responsive genotype (LCG) and a low fat-responsive genotype (LFG). In a preliminary, retrospective study (using the A TO Z weight loss study data), the investigators observed a 3-fold difference in 12-month weight loss for initially overweight women who were determined to have been appropriately matched vs. mismatched to a low carbohydrate (Low Carb) or low fat (Low Fat) diet based on their multi-locus genotype pattern. The primary objective of this study is to confirm and expand on the preliminary results and determine if weight loss success can be increased if the dietary approach (Low Carb vs. Low Fat) is appropriately matched to an individual' s genetic predisposition (Low Carb Genotype vs. Low Fat Genotype) toward those diets.
Primary Outcome
Weight change was calculated as the 12 month value minus the baseline value. The study was designed to determine if either insulin secretion or genotype pattern (low-fat genotype pattern vs .low-carb genotype pattern) were significant effect modifiers of 12-month weight loss for the two diet arms (e.g., 2X2 analyses).
Interventions
- BEHAVIORAL Low-Carbohydrate Diet
- BEHAVIORAL Mobile App
- BEHAVIORAL Low-Fat Diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 609 participants |
| Start Date | 2013-01 |
| Est. Completion | 2016-05 |
| Phase | NA |
What the finished NCT01826591 record still lists
NCT01826591 is an interventional study that assigns participants to a tested intervention. The registered 609 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (57% lower).
The record links to 0 conditions, and to 3 interventions - of which Low-Carbohydrate Diet is the first listed.
NCT01826591 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01826591 about?
NCT01826591 is a clinical study titled "DIETFITS Study (Diet Intervention Examining the Factors Interacting With Treatment Success". Genomics research is advancing rapidly, and links between genes and obesity continue to be discovered and better defined. A growing number of single nucleotide polymorphisms (SNPs) in multiple genes have been shown to alter an individual's response to dietary macronutrient composition. Based on prio...
What is the current status of trial NCT01826591?
This trial is currently completed. It is a NA study. The enrollment target is 609 participants. The study started on 2013-01. Estimated completion is 2016-05.
What interventions are being tested in trial NCT01826591?
The interventions under investigation include: Low-Carbohydrate Diet (BEHAVIORAL), Mobile App (BEHAVIORAL), Low-Fat Diet (BEHAVIORAL).
Who is sponsoring clinical trial NCT01826591?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01826591's enrollment target sits among peer trials
609 162nd of 2000 higher than 1,839 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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