Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01819532 · ClinicalTrials.gov registry record · NA

Milking the Umbilical Cord Versus Immediate Clamping in Pre-term Infants < 33 Weeks

A NA study, sponsored by Johns Hopkins University.

Terminated
Registry status
NA
Development phase
22
Enrollment target

NCT01819532: Clinical Trial NA study, sponsored by Johns Hopkins University.

NCT01819532 is a NA study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 22 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT01819532, a NA study, was terminated before completion, sponsored by Johns Hopkins University.

TERMINATED
Registry status
NA
Development phase
22 participants
Enrollment target

Study Summary

Anemia in preterm neonates is a significant problem encountered frequently in the neonatal intensive care unit. Most preterm neonates born at less than 33 weeks gestation will require at least one blood transfusion during their hospital course and many will require repeated transfusions. Blood transfusions, albeit necessary, carry increased risk of viral infections and transfusion reactions as well as increase the cost of healthcare. The umbilical cord and placenta harbor up to 40% of blood available during fetal life. The current standard of care is immediate umbilical cord clamping. The investigators are performing a randomized controlled trial comparing immediate cord clamping to milking the umbilical cord prior to clamping in neonate born preterm less than 33 weeks gestation. The investigators hypothesize that milking the umbilical cord will demonstrate the same benefits as delayed cord clamping, without delaying neonatal resuscitation.

Interventions

  • PROCEDURE Milking group
  • PROCEDURE Immediate cord clamping

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2011-09
Est. Completion 2013-10
Phase NA
Johns Hopkins University

1,448 total trials

Why NCT01819532 stopped before completion

NCT01819532 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 2 interventions - of which Milking group is the first listed.

NCT01819532 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01819532 about?

NCT01819532 is a clinical study titled "Milking the Umbilical Cord Versus Immediate Clamping in Pre-term Infants < 33 Weeks". Anemia in preterm neonates is a significant problem encountered frequently in the neonatal intensive care unit. Most preterm neonates born at less than 33 weeks gestation will require at least one blood transfusion during their hospital course and many will require repeated transfusions. Blood trans...

What is the current status of trial NCT01819532?

This trial is currently terminated. It is a NA study. The enrollment target is 22 participants. The study started on 2011-09. Estimated completion is 2013-10.

What interventions are being tested in trial NCT01819532?

The interventions under investigation include: Milking group (PROCEDURE), Immediate cord clamping (PROCEDURE).

Who is sponsoring clinical trial NCT01819532?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01819532's enrollment target sits among peer trials

22 1756th of 2000 higher than 239 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02508038 · 22 participants · Phase 1

    Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

  • NCT03099356 · 22 participants · Phase 2

    Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer

  • NCT03676647 · 22 participants

    Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules

  • NCT04569591 · 22 participants · NA

    DDAVP for Pituitary Adenoma

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01819532, the US trial registry maintained by the National Library of Medicine. NCT01819532 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.