Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01817387 · ClinicalTrials.gov registry record · NA

Enhancing Motivation in Recent Onset Schizophrenia

A NA study, sponsored by University of California, San Francisco.

Terminated
Registry status
NA
Development phase
20
Enrollment target

NCT01817387: Clinical Trial NA study, sponsored by University of California, San Francisco.

NCT01817387 is a NA study that was terminated before completion, run by University of California, San Francisco. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01817387, a NA study, was terminated before completion, sponsored by University of California, San Francisco.

TERMINATED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

This project will result in the development of a personalized intervention strategy to improve motivation for treatment engagement and functional outcomes in individuals with a recent onset of schizophrenia. Motivational impairment is arguably the single most important factor that determines a patient's ability to engage in and adhere to effective treatment. In our study, sixty participants will be enrolled in a randomized controlled trial comparing the feasibility and tolerability of two types of motivational interventions (Daily Goals or PRIME), and a neuroplasticity-based cognitive training program. Participants are randomized to either receive Daily Goals or PRIME for 8 weeks, after which, both conditions will also receive an 8-week course of cognitive training delivered via iPads. Participants will undergo pre/post-testing and a 6-month follow-up to determine feasibility and efficacy of the interventions. By enhancing motivation, schizophrenia patients would be able to engage more fully with treatment and develop full and productive lives. This study may also pave the way forward for other health conditions in which motivational impairments impede health outcomes. All assessments will be conducted at the University of California, San Francisco; however, we offer some assessments to be done remotely.

Primary Outcome

Work status, work performance, social status, social performance, health status, health performance

Interventions

  • BEHAVIORAL Cognitive Training
  • BEHAVIORAL PRIME

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2014-07
Est. Completion 2018-03-20
Phase NA

Why NCT01817387 stopped before completion

NCT01817387 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Cognitive Training is the first listed.

NCT01817387 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01817387 about?

NCT01817387 is a clinical study titled "Enhancing Motivation in Recent Onset Schizophrenia". This project will result in the development of a personalized intervention strategy to improve motivation for treatment engagement and functional outcomes in individuals with a recent onset of schizophrenia. Motivational impairment is arguably the single most important factor that determines a patie...

What is the current status of trial NCT01817387?

This trial is currently terminated. It is a NA study. The enrollment target is 20 participants. The study started on 2014-07. Estimated completion is 2018-03-20.

What interventions are being tested in trial NCT01817387?

The interventions under investigation include: Cognitive Training (BEHAVIORAL), PRIME (BEHAVIORAL).

Who is sponsoring clinical trial NCT01817387?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01817387's enrollment target sits among peer trials

20 1768th of 2000 higher than 140 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00573339 · 20 participants

    Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing

  • NCT00692939 · 20 participants · Phase 1

    Autologous Stem Cell Transplantation for Crohn's Disease

  • NCT00967785 · 20 participants · Phase 1

    A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

  • NCT01406691 · 20 participants · Phase 4

    Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01817387, the US trial registry maintained by the National Library of Medicine. NCT01817387 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.